Results 41 to 50 of about 740,964 (300)

Structural Basis of SARS-CoV-2 and SARS-CoV Antibody Interactions

Trends in Immunology, 2020
The 2019 coronavirus pandemic remains a major public health concern. Neutralizing antibodies (nAbs) represent a cutting-edge antiviral strategy. We focus here on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and SARS-CoV, and discuss current progress in antibody research against rampant SARS-CoV-2 infections.
Gavor, Edem, Choong, Yeu Khai, Er, Shi Yin, Sivaraman, Hariharan, Sivaraman, J.   +4 more
openaire   +3 more sources

The SARS-coronavirus-host interactome [PDF]

, 2011
Coronaviruses (CoVs) are important human and animal pathogens that induce fatal respiratory, gastrointestinal and neurological disease. The outbreak of the severe acute respiratory syndrome (SARS) in 2002/2003 has demonstrated human vulnerability to ...
Brunn, Albrecht von, Steffen, Imke, Kögl, Manfred, Schwegmann-Wessels, Christel, Pumpor, Ksenia, Müller, Marcel A., Herzog, Petra, Kuri, Thomas, Ditt, Vanessa, Weber, Friedemann, Schwarz, Frank, Pfefferle, Susanne, Schöpf, Julia, Kallies, Stefan, Herrler, Georg, Carbajo-Lozoya, Javier, Zimmer, Ralf, Hilgenfeld, Rolf, Friedel, Caroline C., Dall'Armi, Ekatarina von, Drosten, Christian, Niemeyer, Daniela, Thiel, Volker, Züst, Roland, Stellberger, Thorsten, Thiel, Heinz-Jürgen, Pöhlmann, Stefan, Haas, Juergen G.   +27 more
core   +1 more source

Subacute thyroiditis after SARS‐CoV‐2 infection

Clinical Case Reports, 2021
Viral infections are considered as etiologic factors of subacute thyroiditis. The true incidence of subacute thyroiditis, caused by SARS‐CoV‐2 infection, is probably considerable since it is often masked by more dramatic affection of the respiratory ...
Vasiliy I. Semikov, Davit L. Aghayan, Alexander M. Shulutko, Tatyana V. Khorobrykh, Yuriy K. Aleksandrov, Gaukhar T. Mansurova, Airazat M. Kazaryan   +6 more
doaj   +1 more source

SARS-CoV-2 Virology

Infectious Disease Clinics of North America, 2022
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first identified in 2020 and has led to an unprecedented global pandemic. Understanding the virology behind SARS-CoV-2 infection has provided key insights into our efforts to develop antiviral agents and control the COVID-19 pandemic.
Li, Yijia, Li, Jonathan Z.
openaire   +3 more sources

Racing for a SARS‐CoV‐2 vaccine

EMBO Molecular Medicine, 2021
Graphical Abstract Interview with EMBO Members Özlem Türeci and Uğur Şahin, BioNTech, conducted by science journalist Kai Kupferschmidt.
Özlem Türeci, Uğur Şahin
doaj   +1 more source

Identification of (20R)-protopanaxadiol from Panax ginseng as a novel anti-SARS-CoV-2 compound. [PDF]

FEBS Open Bio
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Takeda M, Maezono N, Uchikoshi R, Kato N, Ikeda M.   +4 more
europepmc   +2 more sources

Amantadine Inhibits SARS-CoV-2 In Vitro [PDF]

, 2021
Since the SARS-CoV-2 pandemic started in late 2019, the search for protective vaccines and for drug treatments has become mandatory to fight the global health emergency. Travel restrictions,social distancing, and face masks are suitable counter measures,
Danysz, Wojciech, Karl-Heinz Eisele, Marica Grossegesse, Nitsche, Andreas, Grossegesse, Marica, Markus Neumann, FInk, Klaus, Andreas Nitsche, Neumann, Markus, Klaus Fink, Eisele, Karl-Heinz, Wojciech Danysz   +11 more
core   +1 more source

Cardiovascular disease in SARS‐CoV‐2 infection

Clinical & Translational Immunology, 2021
Pre‐existing cardiovascular disease (CVD) increases the morbidity and mortality of COVID‐19 and is strongly associated with poor disease outcomes. However, SARS‐CoV‐2 infection can also trigger de novo acute and chronic cardiovascular disease.
Kei Sato, Jane E Sinclair, Habib Sadeghirad, John F Fraser, Kirsty R Short, Arutha Kulasinghe   +5 more
doaj   +1 more source

Acute parkinsonism secondary to SARS Cov 2 infection. [PDF]

Batna Journal of Medical Sciences, 2023
SARS Cov 2 or Corona virus is a respiratory virus, responsible for a new pandemic since 2019. Main symptoms revolve around respiratory manifestations. Nevertheless, many extra-respiratory attacks are attributed to it.
Mohamed Islam Kediha, Dalila Moualek, Mahdia Hamalit, Lamia Ali Pacha   +3 more
doaj   +1 more source

Immunouniverse of SARS-CoV-2

Immunological Medicine, 2022
SARS-CoV-2 virus has become a global health problem that has caused millions of deaths worldwide. The infection can present with multiple clinical features ranging from asymptomatic or mildly symptomatic patients to patients with severe or critical illness that can even lead to death.
Dennis Jiménez, Marbel Torres Arias
openaire   +3 more sources