Results 311 to 320 of about 1,678,924 (380)

NSP7 Molecular Degrader Attenuates Coronaviral Infection Through the β‐TrCP1/FBXO5 Axis

Advanced Science, EarlyView.
Host E3 ligase FBXO5 as a key regulator that promotes K48‐linked ubiquitination and proteasomal degradation of SARS‐CoV‐2 NSP7, thereby suppressing viral replication. NSP7 ubiquitination is co‐regulated by β‐TrCP1 and TAF1. Small molecule BC24877 disrupts β‐TrCP1‐mediated degradation of FBXO5, stabilizing FBXO5 and enhancing NSP7 clearance ...
Yao Tong, Travis B. Lear, Ferhan Tuncer, John J. Villandre, Áine N. Boudreau, Bo Lin, Irene Alfaras, Jason R. Kennerdell, Daniel P. Camarco, Mads B. Larsen, Yun Hua, Yanwen Chen, Meigin E. Chandler, Ricardo Pineda, Simon M. Barratt‐Boyes, John W. Evankovich, Toren Finkel, Yuan Liu, Bill B. Chen   +18 more
wiley   +1 more source

CONTRIBUTIONÀ L'ÉTUDE DES COPÉPODES HARPACTICOÏDESDE MÉDITERRANÉE OCCIDENTALE.5. STENHELIA (DELAVALIA) COINEAUAE n. s.p.,STENHELIA (D.) BOCQUETI n. s.p.ET TYPHLAMPHIASCUS BOULIGANDI n. s.p.(DIOSACCIDAE, SARS)

, 1971
Jacques Soyer
openalex   +1 more source

Crop discrimination and monitoring with multi-frequency and multi-polarized SAR data : a dryland farming example.

, 1990
C.A. Hutton
openalex   +2 more sources

Performance of Long-Read Single-Molecule Real-Time Sequencing for SARS-CoV-2 Genotyping in Clinical Samples. [PDF]

J Med Virol
Trémeaux P, Latour J, Vellas C, Demmou S, Ranger N, Bal A, Izopet J.   +6 more
europepmc   +1 more source

Unveiling Formation Pathways of Ternary I–III–VI CuInS2 Quantum Dots and Their Effect on Photoelectrochemical Hydrogen Generation

Advanced Science, EarlyView.
The formation pathways of CuInS2 quantum dots are explored through in situ and ex situ characterization. The Lewis acid strength of cation precursors dictates synthesis routes, leading to either indirect or direct nucleation. These routes significantly impact the electrical and photoelectrochemical properties.
Hyo Cheol Lee, Hwapyong Kim, Kiwook Kim, Kyunghoon Lee, Wookjin Chung, Seung Beom Ha, Minseo Kim, Eonhyoung Ahn, Shi Li, Seunghyun Ji, Gyudong Lee, Hyeonjong Ma, Sung Jun Lim, Hongsoo Choi, Jae‐Yup Kim, Hyungju Ahn, Su‐Il In, Jiwoong Yang   +17 more
wiley   +1 more source

Kindlin Regulates Mechanosensitive Activation and Adhesion Assembly of Integrin beta6

Advanced Science, EarlyView.
Extracellular matrix compliance plays a critical role in the regulation of integrin‐mediated adhesion and cell motility. Here, it is reported that strengthening the kindlin2‐integrin β6 interaction overcomes the dependence on extracellular substrate stiffness and promotes integrin β6‐mediated cell migration.
Wan Ning Lee, Jiamin Li, Nan‐Peng Chen, Cheng‐han Yu   +3 more
wiley   +1 more source

CONTRIBUTION A L'ÉTUDEDES COPÉPODES HARPACTICOÏDESDE MÉDITERRANÉE OCCIDENTALE7. LE GENRE BRADYA BOECK(ECTINOSOMIDAE SARS, OLOFSSON).SYSTÉMATIQUE, ÉCOLOGIE

, 1973
Jacques Soyer
openalex   +1 more source

Guidance for preparation of DOE 5480.22 (TSR) and DOE 5480.23 (SAR) implementation plans

, 1994

openalex   +2 more sources

The association between pregnancy outcomes of frozen thawed embryo transfers and previous SARS-CoV-2 infections. [PDF]

Sci Rep
Zhao H, Tian F, Zhang S, Li S, Li N, Zhang J, Mao Z, Zhang Q, Li R, Liang Y, Zhang C, Li Y, Zhao J.   +12 more
europepmc   +1 more source

Osteoblast‐CD4+ CTL Crosstalk Mediated by SIRT1/DAAM2 Axis Prevents Age‐Related Bone Loss

Advanced Science, EarlyView.
In the osteoblastic niche, SIRT1 activates and recruits CD4+ CTLs by increasing DAAM2 expression via EZH2 deacetylation and boosting the secretion of key chemokines, such as CCL3, CCL5, and CXCL10. Then, CD4+ CTL directly eliminates senescent osteoblasts in an MHC‐II‐dependent way, thereby slowing down the process of bone ageing and effectively ...
Bin Yang, Guofu Zhang, Yizhou Zhu, Jingcheng Wang, Xinmin Feng, Wenyong Fei, Jihang Dai, Le Hu, Yi Zhang, Jun Cai, Binjia Ruan, Yue Jin, Fanhao Wei, Gang Lu, Dongan Wang, Jason Pui Yin Cheung, Graham Ka Hon Shea, Hao Chen, Kelvin Wai Kwok Yeung, Lei Wang, Yongxiang Wang   +20 more
wiley   +1 more source