Results 341 to 350 of about 1,678,924 (380)

Analysis of phosphomotifs coupled to phosphoproteome and interactome unveils potential human kinase substrate proteins in SARS-CoV-2. [PDF]

Front Cell Infect Microbiol
Shaji V, Rafi A, Ahmed M, Gopalakrishnan AP, Soman S, Revikumar A, Prasad G, Jayanandan A, Raju R.   +8 more
europepmc   +1 more source

Mucociliary Clearance Inspired Nanozyme‐centric Hydrogel Composites for Integrated Bacterial Detection

Advanced Science, EarlyView.
Inspired by human pulmonary cilia and their mucus defend against bacteria, nanozyme‐centric hydrogel networks have been assembled into nanowires, combining the rapid penetration capability of the nanowire arrays with the adhesion and detection functions of the nanozyme‐centric hydrogel networks.
Zhaoling Tan, Xuejiao Wang, Zhaoyue Wang, Jieke Jiang, Xi Yao   +4 more
wiley   +1 more source

Atypical onset of obsessive-compulsive disorder at age 50 following post-SARS-COV-2 syndrome: A case report. [PDF]

PCN Rep
Sugawara T, Ichiki R.
europepmc   +1 more source

SARS attacks!

Microbes and Infection, 2013
openaire   +1 more source

USP8‐Governed MDA5 Homeostasis Promotes Innate Immunity and Autoimmunity

Advanced Science, EarlyView.
This study reveals that USP8 stabilizes MDA5 via AKT‐mediated phosphorylation (Ser718), enhancing their interaction and MDA5 deubiquitination. USP8 inactivation degrades MDA5, suppressing type I IFN and cytokine production. Pharmacological inhibition of USP8/AKT alleviates MDA5‐driven autoimmunity, demonstrating the USP8‐MDA5 axis as a therapeutic ...
Qimin Zhang, Shan Huang, Yan He, Weiwei Wang, Chao Tong, Mengru Ma, Manyu Zhao, Lian Yi, Klaus‐Peter Knobeloch, Peijing Zhang   +9 more
wiley   +1 more source

NOD2 (Nucleotide-Binding Oligomerization Domain-Containing Protein 2)-Mediated Modulation of the Immune Response Induced by BCG (Bacillus Calmette-Guérin) Bacilli. [PDF]

Pathogens
Jurczak M, Kaczmarek J, Kowalewska-Pietrzak M, Stelmach P, Druszczynska M.   +4 more
europepmc   +1 more source

A Human Immuno‐Lung Organoid Model to Study Macrophage‐Mediated Lung Cell Senescence Upon SARS‐CoV‐2 Infection

Advanced Science, EarlyView.
Immuno‐lung organoids are developed and used spatial transcriptomics to uncover how proinflammatory macrophages drive lung cell senescence via the THBS1–(ITGA3+ITGB1) axis in COVID‐19. To ensure broad accessibility, LungSpatialDB is created, an AI‐powered data portal, enabling intuitive exploration of spatial data and biological insights through ...
Yuling Han, Dongliang Leng, Tuo Zhang, Jian Ge, Yinshan Fang, Tiankun Lu, Xue Dong, Manoj S Nair, Neranjan de Silva, Zhaowei Han, Tiancheng Jiao, Yuanhao Huang, Meiqi Zhao, Anjali Saqi, Hanina Hibshoosh, Zihe Meng, Jenny Z Xiang, Chendong Pan, Yanjie Sun, David D. Ho, Todd Evans, Jie Liu, Liuliu Yang, Jianwen Que, Shuibing Chen   +24 more
wiley   +1 more source

Correlational study between SARS-CoV-2 infection and incidence of situs inversus in China. [PDF]

Orphanet J Rare Dis
Guo Z, Wang R, Yang W, Chen X, Hao B, Liao S.   +5 more
europepmc   +1 more source

Diagnostic accuracy evaluation of a point-of-care antigen test for SARS-CoV-2 and influenza in UK primary care (RAPTOR-C19). [PDF]

PLoS One
Fanshawe TR, Tonner S, Turner PJ, Głogowska M, Ukwatte U, Okusi C, Cogdale J, Zambon M, Nicholson BD, Hobbs FDR, Hayward GN, RAPTOR-C19 Study Group.   +11 more
europepmc   +1 more source