Results 81 to 90 of about 25,096,578 (256)
Deep Contrastive Learning for High‐Throughput Prediction of Drug Resistance Mutations from Sequences
Advanced Science, EarlyView.This study presents DeepMutDTA, a deep learning framework aimed at predicting mutation‐induced changes in protein‐drug interactions and prioritizing variants potentially linked to drug resistance. Trained on large‐scale data, it incorporates SimSiam‐MuTF, a label‐aware contrastive fine‐tuning strategy that encourages separation between WT and MT ...
Xiaowen Hu +7 more
wiley +1 more source
SARS-CoV-2 Prevalence and Variant Surveillance among Cats in Pittsburgh, Pennsylvania, USA
, 2023 Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infects many mammals, and SARS-CoV-2 circulation in nonhuman animals may increase the risk of novel variant emergence.
Shubhada K. Chothe +16 more
core +1 more source
Adult‐onset Still's disease after SARS‐Cov‐2 infection
Clinical Case Reports, 2023 Adult‐onset Still's disease (AOSD) is an uncommon inflammatory disorder. AOSD and SARS‐Cov‐2 infection share clinical and laboratory features, including systemic inflammation.
Tayssir Ben Achour +8 more
doaj +1 more source
Advanced Science, EarlyView.Multidimensional laser‐induced graphene (LIG) spanning from 0D to 3D architectures is comprehensively reviewed for multifunctional biomedical platforms, including biosensing, theranostics, and bioactive interface applications, which highlights its potentials for point‐of‐care diagnostics, wearable health monitoring, smart drug delivery, and tissue ...
Li Zhang +3 more
wiley +1 more source
IgA-Dominant Infection-Associated Glomerulonephritis Following SARS-CoV-2 Infection
, 2021 The renal involvement of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been reported. The etiology of kidney injury appears to be tubular, mainly due to the expression of angiotensin-converting enzyme 2, the key joint receptor for SARS-
Miguel Ángel Solís +9 more
core +1 more source
Acquired immunity against SARS‐CoV‐2 infection and vaccination
EMBO Molecular Medicine, 2023 The ongoing severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) pandemic has caused more than 700 million confirmed infections and ~7 million fatalities worldwide since its emergence in December 2019.
Laurent Renia, Lisa FP Ng
doaj +1 more source
A Generative Neuro‐Symbolic AI for Protein Sequence Design
Advanced Science, EarlyView.We introduce EffieDes, a neuro‐symbolic framework coupling deep learning‐based fitness landscape parameterization with exact automated reasoning. Unlike greedy sampling, EffieDes identifies sequences that globally optimize fitness while satisfying intricate design constraints.
Marianne Defresne +12 more
wiley +1 more source
SARS-CoV-2 Uzbekistan MetaData
, 2022 Tracking temporal and spatial genomic changes and evolution of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Uzbekistan.
Alisher Abdullaev (12124800)
core +1 more source
Infectio, 2022 Objective: To determine the incidence of SARS-CoV-2 infection and its association with sociodemographic, clinical, and occupational characteristics in health workers (HCWs) in the COVID-19 risk area.Material and method: Longitudinal analytical study in a
Milcíades Ibáñez-Pinilla
doaj +1 more source
Advanced Science, EarlyView.Sustained delivery of a shingles subunit vaccine from an injectable polymer–nanoparticle hydrogel enhanced the potency, durability, and breadth of immune responses in aged mice while minimizing inflammatory cytokine production and reactogenicity. This strategy decouples immunogenicity from reactogenicity and offers a promising approach to improve ...
Ye Eun Song +5 more
wiley +1 more source