Results 281 to 290 of about 2,592,842 (396)

Clinical and immunological assessment of asymptomatic SARS-CoV-2 infections

open access: yesNature Medicine, 2020
Quan-xin Long   +18 more
semanticscholar   +1 more source

The evolutionary landscape and serotypic dynamics of avian infectious bronchitis virus from spike protein

open access: yesiMetaOmics, EarlyView.
This study integrates two decades of surveillance with genomic and structural analyses to decipher how spike protein glycosylation haplotypes drive avian coronavirus evolution. We uncover how specific glycosylation patterns associate with receptor‐binding affinity, shape global transmission dynamics, and correlate with clinical outcomes.
Hao Zhang   +21 more
wiley   +1 more source

Diagnostic Concordance of Two‐ and Three‐Gene SARS‐CoV‐2 Molecular Assays in Cameroon: Implications for Efficient Pandemic Response in Low‐ and Middle‐Income Countries

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
This study assessed the interoperability of DaAn Gene, ThermoFisher, and GeneXpert assays used for COVID‐19 testing in Cameroon. GeneXpert showed higher diagnostic performance over ThermoFisher, with all assays having excellent agreement at high viral loads (CT < 20).
Aurelie Minelle Kengni Ngueko   +32 more
wiley   +1 more source

Attention‐deficit hyperactivity disorder in children and young persons during the COVID‐19 pandemic. A temporal trends analysis of electronic heath records in Greater Manchester, England

open access: yesJCPP Advances, EarlyView.
Abstract Background The incidence of attention‐deficit hyperactivity disorder (ADHD) in children and young people has increased in recent years. Disease frequency varies according to sociodemographic characteristics. There are seasonal patterns in ADHD diagnosis and prescribing with rates falling during school holidays.
Louise Hussey   +7 more
wiley   +1 more source

Artificial intelligence strategies for predicting kinase inhibitor resistance: A comprehensive review of methods, challenges, and future perspectives

open access: yesJournal of Intelligent Medicine, EarlyView.
Abstract Kinase inhibitors are essential in targeted cancer therapy, yet resistance often emerges through secondary mutations, activation of compensatory signaling pathways, or drug‐efflux mechanisms. Artificial intelligence (AI) provides a workflow‐based strategy rather than a list of unrelated tools for predicting and addressing kinase‐inhibitor ...
Faris Hassan   +3 more
wiley   +1 more source

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