Results 121 to 130 of about 1,546,592 (273)

Quantifying hope: an EU perspective of rare disease therapeutic space and market dynamics

open access: yesFrontiers in Public Health
Rare diseases, affecting millions globally, pose a significant healthcare burden despite impacting a small population. While approximately 70% of all rare diseases are genetic and often begin in childhood, diagnosis remains slow and only 5% have approved
Emmanuelle Cacoub   +5 more
doaj   +1 more source

Efficacy and Safety Assessment of 5‐Fluorouracil, Irinotecan and Oxaliplatin‐Loaded Implants in Mouse and Pig Models for Pancreatic Cancer Therapy

open access: yesAdvanced Materials, EarlyView.
A novel FIRINOX‐loaded implant demonstrates controlled drug release, and potent therapeutic efficacy in pancreatic ductal adenocarcinoma mouse models with safety confirmed in a large‐animal pre‐clinical model. This innovative drug delivery platform offers a promising new treatment approach for non‐resectable, treatment‐resistant pancreatic cancer ...
Samantha J. Wade   +19 more
wiley   +1 more source

Sas Agapo

open access: yesThe Journal of the Sylvia Townsend Warner Society
An edited presentation of a previously unpublished short story by Sylvia Townsend Warner. A widower’s feelings are stirred by an adder he discovers in his garden. The story is undated but the typewriter suggests a date in the mid- to late 1950s.
doaj   +2 more sources

Activating a Metallization Switch for Record Hydrogen Evolution in Single‐Atom Modified Polar MOF Piezocatalysts

open access: yesAdvanced Materials, EarlyView.
ABSTRACT Piezocatalytic hydrogen evolution enables the conversion of mechanical energy into chemical fuels, but its efficiency is constrained by a trade‐off between piezoelectric polarization and electronic conductivity. Strong piezoelectric polarization is essential for sufficient driving force, yet highly polar materials typically suffer from poor ...
Chongyan Hao   +13 more
wiley   +1 more source

%QLS SAS Macro: A SAS Macro for Analysis of Correlated Data Using Quasi-Least Squares [PDF]

open access: yes
Quasi-least squares (QLS) is an alternative computational approach for estimation of the correlation parameter in the framework of generalized estimating equations (GEE). QLS overcomes some limitations of GEE that were discussed in Crowder (1995).
Han-Joo Kim, Justine Shults
core   +1 more source

Radiotherapy Enhancement by Gold Nanocluster‐functionalized Nanoliposomes Using Polychromatic Orthovoltage X‐ray Irradiation

open access: yesAdvanced Materials Interfaces, EarlyView.
Lipid drug carriers to which ultra‐small gold nanoparticles were added enabled more efficient radiotherapy of cultured pancreatic cancer tumors. These nanoparticles boosted radiation‐induced damage to tumors by generating more reactive molecules, though higher gold levels are needed for strong benefits.
Nazareth Milagros Carigga Gutierrez   +17 more
wiley   +1 more source

SASWeave: Literate Programming Using SAS [PDF]

open access: yes
SASweave is a collection of scripts that allow one to embed SAS code into a LATEX document, and automatically incorporate the results as well. SASweave is patterned after Sweave, which does the same thing for code written in R.
Russell V. Lenth, Søren Højsgaard
core   +1 more source

Mapping of Physiological Signals From Wireless Battery‐Free Implants With Plane‐Wave Ultrasound Imaging

open access: yesAdvanced Materials Technologies, EarlyView.
Combined approach of electromagnetic (Power) and ultrasound (data harvesting) waves is proposed to address the miniaturized ultrasonic implants. Electromagnetic waves trigger the piezoelectric element to generate the acoustic pulse which is modulated by the variations in the sensor's impedance.
Anam Bhatti   +6 more
wiley   +1 more source

From positive projection to delirium. About a case

open access: yesEuropean Psychiatry
Introduction Erotomania, was described in 1942, is more common in women than in men, although the incidence is unknown. This syndrome is usually characterized by a young woman with the illusion that a man whom she considers to be of a higher social or ...
M. V. Barea   +2 more
doaj   +1 more source

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