Development, Optimization, and Evaluation of Nano Self-Emulsifying Drug Delivery System Formulation Platform for Oral Bioavailability Enhancement of Sulfasalazine and Disulfiram in Lung Cancer Chemoprevention. [PDF]
Desai P +7 more
europepmc +1 more source
ABSTRACT Background Pancreatectomy for pancreatic ductal adenocarcinoma (PDAC) with arterial abutment is a complex, high‐risk surgery. We aimed to investigate the clinicopathological features, risk factors, and learning curve for local recurrence after pancreatectomy for PDAC with arterial abutment.
Jun Ishida +9 more
wiley +1 more source
Putative breast cancer risk variants from populations of South Asian ancestry are under-represented in public variant classification databases. [PDF]
Rony R +4 more
europepmc +1 more source
ABSTRACT Background With population aging and extended healthy life expectancy, the management of acute cholecystitis (AC) in patients aged ≥ 85 years has evolved. However, the Tokyo Guidelines 2018 (TG18) for AC provide no specific risk assessment criteria for this population.
Yuta Kobayashi +9 more
wiley +1 more source
Smartphone overuse and its impact on musculoskeletal pain in the neck and wrists/hands in medical and nursing undergraduate students: a cross-sectional study. [PDF]
Phuyal N +3 more
europepmc +1 more source
In a prospective study of 20 elderly gastric cancer patients who declined gastrectomy, laparoscopic and endoscopic cooperative surgery (LECS) was technically safe and preserved postoperative function. However, as oncological curability cannot be assured in advanced cases, careful selection and informed consent are essential.
Marie Washio +9 more
wiley +1 more source
A quantitative, multimodal wearable bioelectronic device for comprehensive stress assessment and sub-classification. [PDF]
Pei X +5 more
europepmc +1 more source
Clinical Significance of Copper Chaperone for Superoxide Dismutase in Colorectal Cancer
ABSTRACT Background Targeting Cu transport proteins is an innovative therapeutic approach for combating cancer. However, the mechanisms underlying the malignant potential of Cu transport proteins remain largely unknown. To address this issue, we focused on the oncogenic potential of copper chaperones for superoxide dismutase (CCS) in colorectal cancer (
Nobuo Takiguchi +15 more
wiley +1 more source
Real-world evaluation of the accuracy of the Viz.AI automated intracranial hemorrhage volume calculation tool. [PDF]
Odland I +16 more
europepmc +1 more source
We assessed the prognostic ability of the Immunoscore and PD‐L1 or PD‐L2 expression in pStage III GC patients by immunohistochemistry. The results showed that Immunoscore was an independent prognostic factor in differentiated GC, but not in undifferentiated GC.
Yoshiro Yukawa +13 more
wiley +1 more source

