Results 231 to 240 of about 574,679 (272)

A hierarchical negative-binomial model for analysis of correlated sequencing data: practical implementations. [PDF]

Bioinform Adv
Górczak K, Burzykowski T, Claesen J.
europepmc   +1 more source

Population Pharmacokinetics of Clesrovimab in Preterm and Full‐Term Infants

Clinical Pharmacology &Therapeutics, EarlyView.
Clesrovimab is a half‐life extended monoclonal antibody targeting the respiratory syncytial virus fusion protein. Three studies (phase Ib/IIa [MK‐1654‐002], phase IIb/III [CLEVER], and phase III [SMART]) were conducted to evaluate the efficacy, safety, and pharmacokinetics (PK) of clesrovimab in infants.
Ziheng Hu, Farina Hellmann, Xiaowei Zang, Nele Plock, Keyur Parmar, Radha A. Railkar, S. Y. Amy Cheung, Brian M. Maas, Ferdous Gheyas   +8 more
wiley   +1 more source

ENOX2 (tNOX)-Associated Stemness in Oral Cancer Cells and Its Clinical Correlation in Head and Neck Tumors. [PDF]

Antioxidants (Basel)
Wang CW, Islam A, Shih YT, Chang CF, Chen MK, Chueh PJ.   +5 more
europepmc   +1 more source

Pharmacogenomics of Major Depressive Disorder in Indigenous Amazonian Populations

Clinical Pharmacology &Therapeutics, EarlyView.
Major depressive disorder is a highly prevalent psychological disorder worldwide and its main treatment is the use of Selective Serotonin Reuptake Inhibitors. However, few studies have demonstrated the relationship between the presence of genetic variants in pharmacogenes and the efficacy of these drugs, especially in populations with a unique genetic ...
Kaio Evandro Cardoso Aguiar, Natasha Monte da Silva, Juliana Carla Gomes Rodrigues, André Maurício Ribeiro‐dos‐Santos, Sandro José de Souza, Ândrea Ribeiro‐dos‐Santos, João Farias Guerreiro, Sidney Emanuel Batista dos Santos, Marianne Rodrigues Fernandes, Ney Pereira Carneiro dos Santos   +9 more
wiley   +1 more source

Use of an augmented reality headset to optimize ergonomics in digestive endoscopy settings. [PDF]

Endoscopy
Grimaldi J, De Cristofaro E, Isman J, Morin F, Masgnaux LJ, Rivory J, Pioche M.   +6 more
europepmc   +1 more source

The β integrin modulates serotonin sensitivity via NPxY motifs to regulate egg laying and mechanosensation behaviors in Caenorhabditis elegans

Developmental Dynamics, EarlyView.
Abstract Background Integrin is an αβ heterodimeric receptor to the extracellular matrix; its binding to the matrix recruits focal adhesions to two NPxY motifs, the tyrosine phosphorylation sites in the cytoplasmic domain. Studies found that replacing tyrosines (Y) with phenylalanines (F) in the motif of β1 integrin displayed little developmental or ...
Josh Haram Bumm, Daniel Dogeon Lee, Zhongqiang Qiu, Angela Haeun Choi, Meghana Kolluri, Michael J. Olsen, Lianzijun Wang, Myeongwoo Lee   +7 more
wiley   +1 more source

ATPase copper transporting beta contributes to cisplatin resistance as a regulatory factor of extracellular vesicles in head and neck squamous cell carcinoma. [PDF]

Cancer Gene Ther
Ogawa T, Ono K, Ryumon S, Kawai H, Sato K, Umemori K, Yoshida K, Obata K, Kunisada Y, Okui T, Okamoto K, Nagatsuka H, Momen-Heravi F, Ibaragi S.   +13 more
europepmc   +1 more source

The correlation between brain structure, function, and cognitive changes in patients with active-stage ulcerative colitis. [PDF]

Front Neurosci
Fan W, Li W, Zhang S, Zhang H, Huang B, Xie X, Wen L, Zhang D.   +7 more
europepmc   +1 more source

Examining the dynamics between loneliness and smartphone addiction among nursing students: A cross-sectional study. [PDF]

Medicine (Baltimore)
Alreshidi SM.
europepmc   +1 more source

N-myristoyltransferase 1-mediated Src Myristoylation Promotes Non-receptor Tyrosine Kinase Pathways in Oral Squamous Cell Carcinoma. [PDF]

In Vivo
Komiyama T, Sugiyama G, Kamohara H, Fujinaga T, Kumamaru W, Moriyama M.   +5 more
europepmc   +1 more source