Results 121 to 130 of about 1,698,061 (303)

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

UNIVERSITIES AS GENERATOR FOR REGIONAL DEVELOPMENT

open access: yesВысшее образование в России, 2016
Some systematic challenges for Russian higher education are considered. Several ways of meeting the challenges are proposed in order to turn regional universities into the centers of regional development.
Andrey V. Belotserkovsky
doaj  

The mediating effect of virtual sharing on the relationship between cyber-ostracism and digital well-being

open access: yese-Kafkas Eğitim Araştırmaları Dergisi
There is increasing evidence that cyber-ostracism adversely affects digital well-being, yet further research is needed to clarify the mechanisms underlying this relationship.
Mustafa Şat
doaj   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

New Procedure for Treatment of Atrial Fibrillation in Patients with Valvular Heart Disease

open access: yesActa Medica Iranica, 2010
Patients with valvular heart disease suffer from atrial fibrillation for more than 12 months after valve surgery and have a low probability of remaining in sinus rhythm. We performed an intra-operative procedure similar to surgical maze ІІІ procedure for
Naser Safaie   +5 more
doaj  

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

PERANAN POLRI DALAM PENANGGULANGAN TINDAK PIDANA PENCURIAN OLEH ANAK (Studi di Wilayah Hukum Kepolisian Resort Kota Medan)

open access: yesJurnal Mercatoria, 2013
Masyarakat saat ini kian menuntut penerapan prinsip tata kelola pemerintahan yang baik (good governance), barangkali tidak berlebihan bila pertanyaan tersebut dikemukakan.
Abdul Hakim, Tan Kamelo
doaj  

The impact of AI integration in project preparation in education course on pre-service teachers’ innovativeness, AI anxiety, attitudes, and acceptance

open access: yesBMC Psychology
The rapid integration of artificial intelligence (AI) in education has transformed teacher education programs. This study examined the effects of incorporating AI tools into a Project Preparation in Education course for pre-service teachers, focusing on ...
Mustafa Sat
doaj   +1 more source

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