Results 171 to 180 of about 137,934 (261)

Explaining EFL students' continuance intention to use e-learning through technology acceptance, expectation confirmation, and flow theory. [PDF]

Sci Rep
Xu X, Yang C.
europepmc   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Matched Analysis of Circulating and Adipose Tissue SIRT1 Protein Level in Human Obesity. [PDF]

Nutrients
Salvatori L, Megiorni F, Baldazzi GM, Ventimiglia V, Gangitano E, Watanabe M, Gandini O, Poggiogalle E, Gnessi L, Lubrano C, Gianfrilli D, Isidori AM, Angeloni A, Mariani S.   +13 more
europepmc   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

COVID-19 pandemic and thyroid diseases. [PDF]

Front Endocrinol (Lausanne)
Irsheid M, Burrack N, Fraenkel M, Hershkovitz E, Yoel U.   +4 more
europepmc   +1 more source

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

FEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara, Takayuki Manabe, Mika Jouta, Kiyoshi Kawasaki   +3 more
wiley   +1 more source

Strong correlation between phantomless and inline phantom-based densitometric calibration of vertebral properties from CT scans of healthy volunteers. [PDF]

Front Bioeng Biotechnol
Gibson FG, Ding Z, Paggiosi MA, Handforth C, Brown JE, Li X, Dall'Ara E, Verbruggen SW.   +7 more
europepmc   +1 more source

SAT-Accel: A Modern SAT Solver on a FPGA

Proceedings of the 2025 ACM/SIGDA International Symposium on Field Programmable Gate Arrays
Michael Lo, Mau-Chung Frank Chang, Jason Cong   +2 more
openaire   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Association learning drives synaptic plasticity at feedforward synapses in somatosensory cortex. [PDF]

Cereb Cortex
Christian JA, Park E, Barth AL.
europepmc   +1 more source