Results 41 to 50 of about 11,140 (252)
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Generating Cryptographic S-Boxes Using the Reinforcement Learning
Substitution boxes (S-boxes) are essential components of many cryptographic primitives. The Dijkstra algorithm, SAT solvers, and heuristic methods have been used to find bitsliced implementations of S-boxes.
Giyoon Kim +4 more
doaj +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Optimizing Test Pattern Compaction with Boolean Satisfiability Attack
Test time per chip plays an essential role in manufacturing tests. Keeping a low number of test patterns becomes one of the prime objectives in concurrence with achieving the desired fault coverage.
Yadi Zhong
doaj +1 more source
Automated Search Oriented to Key Recovery on Ciphers with Linear Key Schedule
Automatic modelling to search distinguishers with high probability covering as many rounds as possible, such as MILP, SAT/SMT, CP models, has become a very popular cryptanalysis topic today.
Lingyue Qin +4 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Full-round impossible differential attack on shadow block cipher
Lightweight block ciphers are the essential encryption algorithm for devices with limited resources. Its goal is to ensure the security of data transmission through resource-constrained devices.
Yuting Liu +3 more
doaj +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
With technical development and internet popularization, Internet of Things (IoT) technology is gaining a wider application in various fields. Key challenges in the growth of IoT are related to privacy and security. To avoid any possible malicious attacks,
Yu He, Gaoli Wang, Wenshan Li, Yizhi Ren
doaj +1 more source

