Results 41 to 50 of about 11,140 (252)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Generating Cryptographic S-Boxes Using the Reinforcement Learning

open access: yesIEEE Access, 2021
Substitution boxes (S-boxes) are essential components of many cryptographic primitives. The Dijkstra algorithm, SAT solvers, and heuristic methods have been used to find bitsliced implementations of S-boxes.
Giyoon Kim   +4 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Optimizing Test Pattern Compaction with Boolean Satisfiability Attack

open access: yesChips
Test time per chip plays an essential role in manufacturing tests. Keeping a low number of test patterns becomes one of the prime objectives in concurrence with achieving the desired fault coverage.
Yadi Zhong
doaj   +1 more source

Automated Search Oriented to Key Recovery on Ciphers with Linear Key Schedule

open access: yesIACR Transactions on Symmetric Cryptology, 2021
Automatic modelling to search distinguishers with high probability covering as many rounds as possible, such as MILP, SAT/SMT, CP models, has become a very popular cryptanalysis topic today.
Lingyue Qin   +4 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Full-round impossible differential attack on shadow block cipher

open access: yesCybersecurity, 2023
Lightweight block ciphers are the essential encryption algorithm for devices with limited resources. Its goal is to ensure the security of data transmission through resource-constrained devices.
Yuting Liu   +3 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Improved Cube Attacks on Some Authenticated Encryption Ciphers and Stream Ciphers in the Internet of Things

open access: yesIEEE Access, 2020
With technical development and internet popularization, Internet of Things (IoT) technology is gaining a wider application in various fields. Key challenges in the growth of IoT are related to privacy and security. To avoid any possible malicious attacks,
Yu He, Gaoli Wang, Wenshan Li, Yizhi Ren
doaj   +1 more source

Home - About - Disclaimer - Privacy