Results 71 to 80 of about 400,990 (266)

Aziridine-Metathesis based Approaches to Alkaloid Synthesis [PDF]

open access: yes, 2009
The aim of the project is to synthesise (-)-morphine utilising aziridine and metathesischemistry. The thesis is divided into three chapters.Chapter 1 provides brief reviews on the subjects of total synthesis of morphine; ringrearrangementmetathesis (RRM)
Lu, Pengfei, Lu, Pengfei
core  

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Improved rotational‐XOR cryptanalysis of Simon‐like block ciphers

open access: yesIET Information Security, 2022
Rotational‐XOR (RX) cryptanalysis is a cryptanalytic method aimed at finding distinguishable statistical properties in Addition‐Rotation‐XOR‐C ciphers, that is, ciphers that can be described only by using modular addition, cyclic rotation, XOR and the ...
Jinyu Lu   +4 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

A logic obfuscation attack method based on gate-level information flow tracing techniques

open access: yesXibei Gongye Daxue Xuebao
Logical obfuscation technique is a mainstream technical means to achieve intellectual property protection and prevent reverse engineering. In this paper, we propose a logical obfuscation attack method based on the gate-level information flow tracking ...
LIU Liang   +5 more
doaj   +1 more source

Cryptanalysis of Reduced-Round SPECK

open access: yesIEEE Access, 2019
SPECK, a family of lightweight block ciphers proposed by the National Security Agency (NSA), is widely used under resource constrained environment. There are many cryptanalytic results on SPECK concentrated on differential and linear attacks.
Jiongjiong Ren, Shaozhen Chen
doaj   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node

open access: yesFEBS Open Bio, EarlyView.
The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner   +6 more
wiley   +1 more source

Quantum Algorithms for Boolean Equation Solving and Quantum Algebraic Attack on Cryptosystems [PDF]

open access: yes, 2018
Decision of whether a Boolean equation system has a solution is an NPC problem and finding a solution is NP hard. In this paper, we present a quantum algorithm to decide whether a Boolean equation system FS has a solution and compute one if FS does have ...
Chen, Yu-Ao, Gao, Xiao-Shan
core   +1 more source

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