Results 41 to 50 of about 1,770,136 (289)

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

M2C-GVIO: motion manifold constraint aided GNSS-visual-inertial odometry for ground vehicles

Satellite Navigation, 2023
Visual-Inertial Odometry (VIO) has been developed from Simultaneous Localization and Mapping (SLAM) as a low-cost and versatile sensor fusion approach and attracted increasing attention in ground vehicle positioning.
Tong Hua, Ling Pei, Tao Li, Jie Yin, Guoqing Liu, Wenxian Yu   +5 more
doaj   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Status, perspectives and trends of satellite navigation

Satellite Navigation, 2020
This paper reviews the status of satellite navigation (as per 11 May 2020)—without claim for completeness—and discusses the various global navigation satellite systems, regional satellite navigation systems and satellite-based augmentation systems ...
Guenter W. Hein
doaj   +1 more source

Analysis of GPS P(Y) signal power enhancement based on the observations with a semi-codeless receiver

Satellite Navigation, 2022
The Global Position System (GPS) satellites of Block IIR-M and later versions can turn on the signal power enhancement if needed. In recent years, this power enhancement has been triggered several times when the U.S force was involved in local conflicts,
Xiaomei Tang, Muzi Yuan, Feixue Wang
doaj   +1 more source

A bioinformatics screen identifies TCF19 as an aggressiveness‐sustaining gene in prostate cancer

Molecular Oncology, EarlyView.
Gene expression meta‐analysis in multiple prostate cancer patient cohorts identifies Transcription factor 19 (TCF19) as an aggressiveness‐sustaining gene with prognostic potential. TCF19 is a gene repressed by androgen signaling that sustains core cancer‐related processes such as vascular permeability or tumor growth and metastasis.
Amaia Ercilla, Jana R. Crespo, Saioa Garcia‐Longarte, Marta Fidalgo, Sara del Palacio, Natalia Martin‐Martin, Onintza Carlevaris, Ianire Astobiza, Sonia Fernández‐Ruiz, Marc Guiu, Laura Bárcena, Isabel Mendizabal, Ana M. Aransay, Mariona Graupera, Roger R. Gomis, Arkaitz Carracedo   +15 more
wiley   +1 more source

Refining the ERA5-based global model for vertical adjustment of zenith tropospheric delay

Satellite Navigation, 2022
Tropospheric delay is an important factor affecting high precision Global Navigation Satellite System (GNSS) positioning and also the basic data for GNSS atmospheric research.
Ge Zhu, Liangke Huang, Yunzhen Yang, Junyu Li, Lv Zhou, Lilong Liu   +5 more
doaj   +1 more source

Estimating rainfall and water balance over the Okavango River Basin for hydrological applications [PDF]

, 2006
A historical database for use in rainfall-runoff modeling of the Okavango River Basin in Southwest Africa is presented. The work has relevance for similar data-sparse regions.
Adeyewa, Adler, Brath, Cornelis Vanderpost, Denis Hughes, Dominic Kniveton, Gan, Grimes, Haddad, Julie Wilk, Kummerow, Kummerow, Kummerow, Lebel, Lotta Andersson, Martin C. Todd, McCarthy, Nash, Negri, New, Oki, Russell Layberry, Susan Ringrose, Weber, Wilk   +24 more
core   +2 more sources

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

A power controller integrating MPPT and S3R topology

Dianzi Jishu Yingyong
Satellite power systems using direct energy transmission have the advantages of simple circuit structure and high reliability, but the solar array energy utilization rate is low. In contrast, using maximum power point tracking technology can maximize the
Wang Boxin, Liu Shufeng, Zou Jiwei, Jia Xu, Zhang Wei, Dai Lu   +5 more
doaj   +1 more source