Results 161 to 170 of about 349 (223)

A 3D Human Bone and Bone Marrow‐on‐a‐Chip Model for In Vitro Bone Remodeling and Immune Cell Maintenance

Advanced Science, EarlyView.
This study presents a human Bone (and Bone Marrow)‐on‐a‐Chip model based on native human bone scaffolds and autologous cells. Dynamic perfusion and sequential cell seeding replicate the physiological bone remodeling process in vitro, enabling the long‐term culture of functional, mature bone marrow immune subpopulations.
Nina Stelzer, Melanie‐Jasmin Ort, Kristian Händler, Emely Bortel, Ioanna Maria Dimitriou, Martin Textor, Georg N. Duda, Janosch Schoon, Uwe Marx, Uwe Kornak, Annika Winter, Bernhard Hesse, Stefanie Donner, Sebastian Hardt, Oliver Klein, Simon Reinke, Malte Spielmann, Sven Geißler   +17 more
wiley   +1 more source

Modulation of miR‐23b Wnt/β‐catenin Axis Strengthens Endothelial Barrier Properties

Advanced Science, EarlyView.
Early blood‐brain barrier (BBB) disruption contributes to stroke and CNS disease pathology. miR‐23b was identified as a regulator of BBB integrity in brain endothelial cells. Inhibition of miR‐23b enhanced barrier‐associated properties, promoted repair‐related signaling, and reduced BBB leakage in experimental stroke models, supporting further ...
Victor Anthony Martinez, Rose E. Presby, Sara Nakanishi, Pallavi Gaur, Ugur Akcan, Johannes Daugaard Krog, Iben Daugaard Krog, Lipi Das, David S. Johnson, Danny Jamoul, Douglas Jury, Brian Lawson, Jacob Körbelin, Lewis M. Brown, Vilas Menon, Dritan Agalliu, Irene Munk Pedersen   +16 more
wiley   +1 more source

PRC2.1 Coordinates Peri‐Nucleolar H3K27me3‐Enriched Heterochromatin Organization and NPM1 Pentamerization to Maintain Nucleolar Integrity

Advanced Science, EarlyView.
PRC2.1(PCL2)‐coordinated H3K27me3‐enriched PNH establishes a spatial scaffold crucial for nucleolar integrity. As a crucial coordinator, PCL2 links PRC2.1 to chromatin organization and NPM1 assembly. This network‐based model reveals how chromatin modifications and nucleolar components cooperatively maintain nucleolar architecture, revealing novel ...
Lina Zhu, Wenqin Wang, Shuyun Chen, Gangyi Zhu, Zhen Wu, Yue Gu, Jingwen Xiong, Xu Zhang, Heng Liu, Kyoichi Isono, Youming Zhang, Jingjing Cao, Xiangzhi Li   +12 more
wiley   +1 more source

A Toolkit for Targeted Neuromodulation of Striatal Direct Pathway Neurons Rescues Parkinsonian Motor Deficits in Mice

Advanced Science, EarlyView.
An adeno‐associated virus (AAV) toolkit enables selective anatomical and functional targeting of striatal D1‐MSNs through retrograde transduction. Enhanced capsids and engineered enhancers drive robust transgene expression across murine and primate models.
Zexuan Hong, Yujing Zhang, Junjiao Zhang, Hanhe Liu, Qiwei Liu, Yanglei Li, Lixin Yang, Lixia Li, Zhongjie Liu, Zhen Yuan, Zhonghua Lu, Yefei Chen, Yuantao Li, Yuwu Jiang, Taian Liu   +14 more
wiley   +1 more source

Synthesis and Characterization of λ-Carrageenan Oligosaccharide-Based Nanoparticles: Applications in MRI and In Vivo Biodistribution Studies. [PDF]

Biomacromolecules
Porta-Zapata M, Carregal-Romero S, Saliba J, Urkola-Arsuaga A, Miranda Perez de Alejo CB, Orue I, Martínez-Parra L, Di Silvio D, Descamps-Mandine A, Daviaud C, Menard M, Hamami A, Musnier B, Cherfan J, Codault A, Manseur C, Jeannin M, Castejón D, Fruitier-Arnaudin I, Ruiz-Cabello J, Groult H.   +20 more
europepmc   +1 more source

Nickel-Induced Reduced Graphene Oxide Nanoribbon Formation on Highly Ordered Pyrolytic Graphite for Electronic and Magnetic Applications. [PDF]

ACS Appl Nano Mater
Luis-Sunga M, González-Orive A, Calderón JC, Gamba I, Ródenas A, de Los Arcos T, Hernández-Creus A, Grundmeier G, Pastor E, García G.   +9 more
europepmc   +1 more source

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Magnetic attitude control of a spinning satellite

1st Annual Meeting, 1964
Design of a self-contained magnetic attitude control system for a spinning satellite is described, and particular control techniques for sensing and actuation are developed. A specific control problem associated with the alignment of spin axis normal to the orbit plane in the presence of external perturbations is examined in detail, and a simple ...
E. I. ERGIN, P. C. WHEELER
openaire   +1 more source

Robust Magnetic Attitude Control of Satellites

IEEE/ASME Transactions on Mechatronics, 2013
Magnetic torquers are frequently adopted as primary actuators for the attitude control of small satellites in low Earth orbit. Such actuators generate a magnetic dipole which, in turn, leads to control torques thanks to the interaction with the magnetic field of the Earth.
ZANCHETTIN, ANDREA MARIA, A. Calloni, LOVERA, MARCO   +2 more
openaire   +2 more sources

Magnetic satellites in mictomagnetic CuMn

Journal of Physics F: Metal Physics, 1983
The neutron scattering intensities about the 11/20 diffuse peak, in 15 and 40 at.% CuMn single crystals have been investigated. It is suggested that the maxima in the diffuse magnetic scattering intensity, which occurs at 1, 1+or- delta ', 0 type positions, is caused by an interaction with the conduction electrons.
T M Harders, P Wells
openaire   +1 more source

Analysis of Satellite Magnetic Data

Exploration Geophysics, 2005
Night-time measurements of the Earth?s undisturbed, quiet magnetic field at satellite altitudes provide models of the main field and its secular variation, and of the crustal magnetic anomaly field. Fields from the regular daily variations of solar and lunar origin are most pronounced in daytime data and can affect aeromagnetic and ground magnetic ...
Jon Turner, Denis Winch, David Ivers, Robert Stening   +3 more
openaire   +1 more source