Results 151 to 160 of about 30,945 (217)

Bacteria‐Derived 1‐Allylpiperazine Alleviates Symptoms of Parkinson's Disease Model by Promoting Autophagy

open access: yesAdvanced Science, EarlyView.
Parkinson's disease currently has no disease‐modifying therapies. In Caenorhabditis elegans, Escherichia coli E8 alleviates α‐synuclein‐provoked PD‐related defects through its bioactive metabolite 1‐ALPP, which combats PD by triggering AMPK/mTOR/HLH‐30‐dependent autophagy and suppressing α‐synuclein LLPS‐mediated fibrillization.
Mingqin Qu   +12 more
wiley   +1 more source

Tropical Wetland Methane Emissions and Trends (2004-2023) Inferred from Landsat-Based Inundated Vegetation Data. [PDF]

open access: yesEnviron Sci Technol
Chen Z   +11 more
europepmc   +1 more source

LLM‐Assisted Design of Ultralow‐κ$\kappa$ Chalcogenides

open access: yesAdvanced Science, EarlyView.
An AI assisted, physics guided workflow accelerates the discovery of ultralow thermal conductivity materials by combining Bayesian optimization, evidence conditioned LLM reasoning, and automated physics‐based validation. The framework uncovers dynamically stable Ag based chalcogenides with ultralow thermal conductivity and promising thermoelectric ...
Yujie Liu   +9 more
wiley   +1 more source

Decorrelating carbon and water fluxes in the Amazon Basin. [PDF]

open access: yesNat Commun
Worden S   +5 more
europepmc   +1 more source

Low‐Density Lipoprotein Receptor‐Targeted Biomimetic Nanoplatform Suppresses Glioblastoma Stemness and Remodels Antitumor Immunity via Dual Metabolic Disruption

open access: yesAdvanced Science, EarlyView.
A low‐density lipoprotein receptor‐oriented biomimetic nanoplatform couples brain‐tumor delivery with a mechanistically matched regorafenib‐erythrodiol combination. Concurrent disruption of autophagic nutrient salvage and cholesterol homeostasis collapses bioenergetic and signaling support, suppresses glioblastoma stemness, and promotes immunogenic ...
Yining Jiang   +12 more
wiley   +1 more source

Mechanochemical Engineered Sulfur Copolymers Onto Group 13 and Related Fillers Through Lewis Acid‐Base Pairing

open access: yesAdvanced Science, EarlyView.
Green mechanochemical copolymerization was developed for universal interfacial modification of Group 13 and related fillers. By leveraging Lewis acid–base coordination to anchor sulfur‐containing polymers—validated via multiscale characterization and DFT—this versatile method boosts performance across liquid fuels, thermal‐shielding materials, and ...
Chen Wang   +7 more
wiley   +1 more source

Ionically Counter‐Programmable Phase‐Separation of Superstable Star‐Biopolyamide Coacervates for Electrothermally‐Responsive Pseudosolid Smart Windows

open access: yesAdvanced Science, EarlyView.
We develop bio‐based, star‐branched polyamides from itaconic acid and cadaverine with tunable lower critical solution temperature (LCST) transitions for dynamic solar modulation. Specific metal ion coordination with pyrrolidone moieties drives precise phase transitions via calcium‐induced salting‐in and sodium‐induced salting‐out mechanisms. Formulated
Jie Liu   +6 more
wiley   +1 more source

Rapid Solidification Brings Ultralow Thermal Conductivity and Superior Thermoelectric Performance for Intrinsic GeTe Alloy

open access: yesAdvanced Science, EarlyView.
Rapid solidification with glass fluxing is first applied to the intrinsic GeTe alloy and achieves large undercooling within 2 h. This enables partial retention of the high‐temperature cubic phase at room temperature and forms a crystallographically oriented α+β dual‐phase structure and a hierarchical defect network.
Guanghui Liu   +4 more
wiley   +1 more source

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