Results 61 to 70 of about 24,143,953 (388)

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Use of Cyclone Global Navigation Satellite System (CyGNSS) Observations for Estimation of Soil Moisture

Geophysical Research Letters, 2018
Using the first full annual cycle of Cyclone Global Navigation Satellite System (CyGNSS) observations, we investigated the limitations and capabilities of CyGNSS observations for soil moisture (SM) estimates (0–5 cm).
Hyunglok Kim, V. Lakshmi
semanticscholar   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Technical approbation of the method for testing on vibration effects of on-board radio-electronic equipment of spacecrafts [PDF]

Космические аппараты и технологии
The article provides a description of the developed method, which ensures the correct realization of mechanical tests of on-board radio-electronic equipment of spacecrafts for vibration effects in the process of ground experimental testing.
A. А. Khvalko, A. S. Orlov, S. B. Suntsov, I. S. Vasiliev, A. A. Goryainova   +4 more
doaj  

How Can Microwave Observations at 23.8 GHz Help in Acquiring Water Vapor in the Atmosphere over Land?

Remote Sensing, 2021
Due to concerns about radio frequency interference from emerging telecommunications technology, there have been intensive discussions on the changes to the international Radio Regulations around 24 GHz at the recent World Radiocommunication Conference in
Quanhua (Mark) Liu, Changyong Cao, Christopher Grassotti, Yong-Keun Lee   +3 more
doaj   +1 more source

Dynamic Limits on Planar Libration-Orbit Coupling Around an Oblate Primary

, 2012
This paper explores the dynamic properties of the planar system of an ellipsoidal satellite in an equatorial orbit about an oblate primary. In particular, we investigate the conditions for which the satellite is bound in librational motion or when the ...
CM Hartzel, DA Mendis, David Richardson, DJ Griffiths, DJ Scheeres, DJ Scheeres, Douglas Mathews, DR Criswell, EG Fahnestock, ES Gawlik, F Gabern, Gina Ma, J Bellerose, Jared M. Maruskin, JE Colwell, Julie Bellerose, Lara Mitchell, Macken Wong, P Lee, RA Werner, TJ Linde, Tri Nguyen, Usha Ganeshalingam, V Guibout, X Wang, Y Nakajima   +25 more
core   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Culture conditions influence satellite cell activation and survival of single myofibers [PDF]

, 2018
Single myofiber isolation protocols allow to obtain an in vitro system in which the physical association between the myofiber and its stem cells, the satellite cells, is adequately preserved.
Adamo, Sergio, Benedetti, Anna, Bouche', Marina, Moresi, Viviana, Renzini, Alessandra, Silvestroni, Leopoldo   +5 more
core   +2 more sources

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source