Results 221 to 230 of about 17,769 (298)

Integrative host–microbiome modeling uncovers the implication of oral–gut translocation in advanced cirrhosis

open access: yesiMeta, EarlyView.
Liver cirrhosis is associated with profound disruption of host–microbiome metabolic interactions. Using paired oral and fecal metagenomics combined with genome‐scale metabolic modeling, we investigated how microbial translocation along the oral–gut axis influences microbial metabolism at different cirrhosis severities.
Yi Jin   +21 more
wiley   +1 more source

Enviromics crosstalk between internal and external plant environments for enhanced adaptation and de novo domestication

open access: yesiMeta, EarlyView.
Climate change demands accelerated plant adaptation and de novo domestication. Yet current enviromics focuses disproportionately on external environments, neglecting internal dynamics—gene expression, metabolic flux, and signal transduction—within predictive envirotyping frameworks.
Lin‐An Zhang   +8 more
wiley   +1 more source

Bowhead whale foraging dives are defined by speed and body orientation. [PDF]

open access: yesPLoS One
den Haan MF   +5 more
europepmc   +1 more source

Microbial metabolite indole‐3‐propionic acid preserves astrocytic mitochondrial mitofusin 2 to limit neuroinflammation after traumatic brain injury

open access: yesInterdisciplinary Medicine, EarlyView.
Following traumatic brain injury, indole‐3‐propionic acid (IPA) directly targets the aryl hydrocarbon receptor on astrocytes in the peri‐lesional cortex; this suppresses interferon regulatory factor 1‐driven transcription of the E3 ubiquitin ligase RFFL (ring finger and FYVE‐like domain containing E3 ubiquitin protein ligase).
Ziwen Zhang   +22 more
wiley   +1 more source

Nature‐Based and Community‐Level Responses to Climate Distress in Young People: A Systematic Review

open access: yesJournal of Adolescence, EarlyView.
ABSTRACT Introduction Climate change is both an environmental crisis and a growing source of psychological distress for young people, calling for responses that nurture emotional resilience and collective engagement. The emerging response to climate distress has mainly focused on formal psychological and individual‐level interventions.
Meghana Bhupati   +3 more
wiley   +1 more source

Experiences of patients with complex needs at municipal emergency outpost satellites. [PDF]

open access: yesScand J Prim Health Care
Østerbø T   +5 more
europepmc   +1 more source

Comparative Evaluation of Four Stereotactic Radiosurgery Planning Approaches for Treatment of Posterior Choroidal Melanoma

open access: yesJournal of Medical Radiation Sciences, EarlyView.
This study evaluated four stereotactic radiosurgery planning approaches for posterior choroidal melanoma (CM). Analysis of thirteen CM cases resulted in a clinically meaningful reduction in dose to the brain for Brainlab Elements modulated arcs (BE) and Varian Eclipse HyperArc modulated arcs (HA) compared to Brainlab iPlan dynamic conformal arc therapy
Robert Nigro   +5 more
wiley   +1 more source

Optical Skyrmions with Tunable or Reconfigurable Topology Using Spin‐Decoupled Metaoptics

open access: yesLaser &Photonics Reviews, EarlyView.
The work introduces advanced optical elements capable of generating and dynamically reconfiguring complex light patterns known as optical skyrmions. By precisely shaping light polarization at the nanoscale, a single engineered metasurface can generate and manipulate robust and tunable polarization textures in an efficient and scalable way.
Andrea Vogliardi   +5 more
wiley   +1 more source

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