Results 91 to 100 of about 26,640 (343)

Electrocortical N400 Effects of Semantic Satiation

Frontiers in Psychology, 2017
Semantic satiation is characterised by the subjective and temporary loss of meaning after high repetition of a prime word. To study the nature of this effect, previous electroencephalography (EEG) research recorded the N400, an ERP component that is ...
Kim Ströberg, Lau M. Andersen, Stefan Wiens   +2 more
doaj   +1 more source

Pathological Disulfide Bond Crosslinking: Molecular Insights into Amyloidogenesis and Diseases Progression

ChemBioChem, EarlyView.
This review explores pathological disulfide‐crosslinking as a key driver of amyloidogenic protein misfolding and aggregation. Oxidative and ER stress pathways contributing to disease progression are discussed and emerging therapeutic strategies targeting disulfide‐linked aggregates in neurodegenerative and systemic amyloid diseases are examined ...
Dong Min Kang, Nataliia Lukianenko, Ja‐Hyun Baik, Yun Kyung Kim, Sungsu Lim   +4 more
wiley   +1 more source

A Pharmacometric Method for Quantitative Determination of Improvement in Body Composition and Characterization of the Exposure–Response Relationship during Treatment of Obesity with Tirzepatide

Clinical Pharmacology &Therapeutics, EarlyView.
About half of the world's population is living with overweight or obesity. Tirzepatide is an approved treatment for chronic weight management. We sought to characterize the exposure–response relationship for weight reduction in patients with overweight or obesity and quantify the associated changes in body composition.
Emmanuel Chigutsa, Lucy Her, Xiaosu Ma, Shweta Urva, Karen Schneck   +4 more
wiley   +1 more source

The Public Sphere as a Meaningful Arena for Volunteering Dynamics: The Case of a Rural Space in Northern Israel

Conflict Resolution Quarterly, EarlyView.
ABSTRACT This article examines the context of the rural public sphere as reflected in residents' consciousness of their volunteering potential. To this end, a qualitative study was conducted in two rural settlements belonging to the same regional municipality in northern Israel: one Jewish and the other Arab. The 32 interviewees who participated in the
Yasmin Aboud‐Halabi, Galit Yanay‐Ventura   +1 more
wiley   +1 more source

Determinantes dietéticos da ingestão alimentar e efeito na regulação do peso corporal

Archivos Latinoamericanos de Nutrición, 2003
RESUMO. A obesidade é uma patologia multicausal, considerada, atualmente, como um dos principais problemas de saúde pública. Sua prevalência vem crescendo muito nas últimas décadas alcançando índices alarmantes no Brasil e no mundo.
Luciana Neri Nobre, Josefina Bressan Resende Monteiro   +1 more
doaj  

Mesolimbic Dopamine Encodes Prediction Errors in a State-Dependent Manner

Cell Reports, 2016
Mesolimbic dopamine encodes the benefits of a course of action. However, the value of an appetitive reward depends strongly on an animal’s current state.
Georgios K. Papageorgiou, Mathieu Baudonnat, Flavia Cucca, Mark E. Walton   +3 more
doaj   +1 more source

Moderate to Vigorous Physical Activity as a Cause of Dietary Restriction in Eating Disorders

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective The mechanisms that facilitate prolonged dietary restriction in eating disorders, particularly in the absence of binge eating, remain poorly understood. The activity‐based anorexia model and basic science in exercise physiology suggest that moderate to vigorous physical activity leads to reduced energy intake relative to metabolic ...
K. Jean Forney, Angela R. Hillman, Lindsay P. Bodell   +2 more
wiley   +1 more source

Commonalities of platelet dysfunction in heart failure with preserved ejection fraction and underlying comorbidities

ESC Heart Failure, Volume 12, Issue 2, Page 1013-1028, April 2025.
Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia, Blanche Schroen, Judith M.E.M. Cosemans   +2 more
wiley   +1 more source

Implementation of guideline‐recommended medical therapy for patients with heart failure in Europe

ESC Heart Failure, Volume 12, Issue 2, Page 790-798, April 2025.
Abstract Physicians' adherence to guideline‐recommended heart failure (HF) treatment remains suboptimal, especially regarding the target doses. In particular, there is evidence that non‐cardiologists are less compliant with HF guideline recommendations. This is likely to have a detrimental impact on patients' survival, readmissions and quality of life.
Maurizio Volterrani, Petar Seferovic, Gianluigi Savarese, Ilaria Spoletini, Egidio Imbalzano, Antoni Bayes‐Genis, Ewa Jankowska, Michele Senni, Marco Metra, Ovidiu Chioncel, Andrew J. S. Coats, Giuseppe M. C. Rosano   +11 more
wiley   +1 more source

Why plankton modellers should reconsider using rectangular hyperbolic (Michaelis-Menten, Monod) descriptions of predator-prey interactions

Frontiers in Marine Science, 2016
Rectangular hyperbolic type 2 (RHt2; Michaelis-Menten or Monod -like) functions are commonly used to describe predation kinetics in plankton models, either alone or together with a prey selectivity algorithm deploying the same half-saturation constant ...
Kevin John Flynn, Aditee Mitra
doaj   +1 more source