Results 181 to 190 of about 49,113 (338)

Targeted Next‐Generation Sequencing of the Leptin‐Melanocortin Pathway in Severe Obesity

open access: yesObesity, EarlyView.
ABSTRACT Objective Pathogenic variants in five established leptin‐melanocortin pathway genes (LEP, LEPR, MC4R, PCSK1, POMC) are associated with severe early‐onset obesity and are targets for emerging treatments. However, these variants are rare in these patients, suggesting the involvement of additional genes interacting with this pathway. Methods Next‐
Nathan Faccioli   +12 more
wiley   +1 more source

Addition of Phentermine‐Topiramate to a Digitally Enhanced Lifestyle Intervention: A Double‐Blind Randomized Clinical Trial

open access: yesObesity, EarlyView.
ABSTRACT Objective This study compared the effects of phentermine‐topiramate‐ER (mid‐dose 7.5/46 mg) versus placebo on weight loss and cardiovascular disease (CVD) risk outcomes when used as an adjunct to a digitally enhanced lifestyle intervention (DELI).
Alejandro Campos   +15 more
wiley   +1 more source

Co-Development of Infant Satiation Cues and Maternal Feeding Behaviors during Infancy. [PDF]

open access: yesCurr Dev Nutr
Ventura AK   +5 more
europepmc   +1 more source

Key Determinants of Weight Loss Trajectory Across Different Periods of a Behavioral Weight Loss Intervention

open access: yesObesity, EarlyView.
ABSTRACT Objective This longitudinal study aims to identify the key factors influencing the weight loss trajectory during a 24‐week intervention and their relevance at different stages of the treatment. Methods We studied 1252 participants (age 18–65 years) of a cognitive behavioral program to lose weight.
Rocío De la Peña‐Armada   +4 more
wiley   +1 more source

Physical Activity and Prevalence of Functional Dyspepsia in Adults: A Cross-Sectional Study. [PDF]

open access: yesInt J Prev Med
Tavasoli P   +7 more
europepmc   +1 more source

Psychiatric Safety of Tirzepatide in People With Obesity and No Known Major Psychopathology: A Post Hoc Analysis of SURMOUNT

open access: yesObesity, EarlyView.
ABSTRACT Objective This post hoc analysis assessed psychiatric changes with tirzepatide in adults with obesity, without known major psychopathology, from SURMOUNT‐1, SURMOUNT‐2, and SURMOUNT‐3. Methods In participants (N = 4056) treated with tirzepatide (5/10/15 mg or maximum tolerated dose 10/15 mg) versus placebo, depressive symptoms and suicidal ...
Thomas A. Wadden   +6 more
wiley   +1 more source

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