Results 271 to 280 of about 49,113 (338)

Novel therapeutic targets for chronic visceral pain in gastrointestinal disorders

British Journal of Pharmacology, EarlyView.
Chronic visceral pain imposes a major clinical challenge in gastroenterology and beyond, profoundly impacting patients' quality of life. However, limited understanding of its complex, multifaceted pathophysiology, encompassing both peripheral and central mechanisms, continues to impede the development of effective management strategies.
Fleur Veldman, Christopher J. Black, Andrea Shin, Daniel Keszthelyi   +3 more
wiley   +1 more source

The return of metabolism: biochemistry and physiology of glycolysis

Biological Reviews, EarlyView.
ABSTRACT Glycolysis is a fundamental metabolic pathway central to the bioenergetics and physiology of virtually all living organisms. In this comprehensive review, we explore the intricate biochemical principles and evolutionary origins of glycolytic pathways, from the classical Embden–Meyerhof–Parnas (EMP) pathway in humans to various prokaryotic and ...
Nana‐Maria Grüning, Federica Agostini, Camila Caldana, Johannes Hartl, Matthias Heinemann, Markus A. Keller, Jan Lukas Krüsemann, Costanza Lamperti, Carole L. Linster, Steffen N. Lindner, Julia Muenzner, Jens Nielsen, Zoran Nikoloski, Bettina Siebers, Jacky L. Snoep, Hezi Tenenboim, Bas Teusink, Spencer J. Williams, Mirjam M. C. Wamelink, Markus Ralser   +19 more
wiley   +1 more source

Pharmacotherapy for Obesity: Recent Updates. [PDF]

Clin Pharmacol
Fredrick TW, Camilleri M, Acosta A.
europepmc   +1 more source

After 50 Years of ‘Protocolization’, What Is the Progress Towards Munro's Image of a More Flexible, Innovative and ‘Child‐Centred’ English Child Protection System?

Child &Family Social Work, EarlyView.
ABSTRACT Fifty years after the formation of England's child protection system, the country continues to reel from new instances of high‐profile child death tragedies where children have been harmed despite practitioners complying with the processes and procedures designed to protect them.
Ciarán Murphy, Michael Murphy
wiley   +1 more source

Roux-en-Y Gastric Bypass Reduces Preprandial Appetite and Energy Intake Without Altering Relative Macronutrient Intake

Bueter M, Alceste D, Jucker N, Burgh Yvd, File B, Thalheimer A, Steinert R, Spector A, Maurer S, Hazebroek E, Gero D, Serra M.   +11 more
europepmc   +1 more source

Parental social environment has transgenerational effects on zebrafish (Danio rerio) growth. [PDF]

Sci Rep
Dissinger A, Kwasek K.
europepmc   +1 more source

Satiation and recovery of the exploratory drive as a function of environmental complexity and trial length

, 1966
Robert B. Graham
openalex   +1 more source

Expansion of the Phenotypic and Genotypic Spectrum for PRKAR1B‐Related Marbach–Schaaf Neurodevelopmental Syndrome: A Case Series

Clinical Genetics, EarlyView.
Comprehensive clinical description of 12 subjects with pathogenic PRKAR1B variants, including two heterozygous deletions supporting haploinsufficiency as a possible mechanism of disease, providing valuable insight into the pathophysiology of MASNS and setting a framework upon which to design future mechanistic studies of PKA signaling in brain ...
Sebastian Burkart, Tarik Guzeloglu, Ana R. Soares, Irene Valenzuela, Eduardo F. Tizzano, David Gómez‐Andres, Laurent Pasquier, Marine Legendre, Camille Berges, Julien Thevenon, Marjolaine Gauthier, Caleb Heid, Elly Ranum, Joseph Shen, Michelle Frees, Michael W. Schmidtke, Caro Pilar, Christian P. Schaaf   +17 more
wiley   +1 more source

Impact of a mineral enriched, fiber complex on glycaemic response and satiation in healthy adults: a double-blind, crossover intervention study. [PDF]

Eur J Nutr
Ancu O, Mackenzie RWA, Patterson M, Dsilva E, Yakubov GE, Haynes M, Kolida S, Stephenson CG, Costabile A.   +8 more
europepmc   +1 more source

Changes in gastrointestinal motility and gut hormone secretion after Roux‐en‐Y gastric bypass and sleeve gastrectomy for individuals with severe obesity

Clinical Obesity, Volume 15, Issue 2, April 2025.
Summary Background Bariatric surgery is very effective in long‐term weight management. The present study was undertaken to investigate the short‐term effects of sleeve gastrectomy (SG) and of Roux‐en‐Y gastric bypass (RYGB) on (a) gastrointestinal (GI) motility, that is gastric emptying and oro‐cecal transit time and (b) secretion of regulatory gut ...
Jennifer A. Wilbrink, Mark van Avesaat, Simon W. Nienhuijs, Arnold Stronkhorst, Ad A. M. Masclee   +4 more
wiley   +1 more source