Weight Loss With GLP‐1 Agonists in Nondiabetic Adults: Systematic Review and Network Meta‐Analysis
ABSTRACT Objective Two glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) (semaglutide and liraglutide) and one dual agonist (tirzepatide) are FDA‐approved for weight loss in adults with obesity without type 2 diabetes mellitus. This systematic review and network meta‐analysis aims to compare the efficacy of these agents against each other.
Michael Lim +3 more
wiley +1 more source
Obesogenic effects of warm temperature involve feeding adaptation by preoptic area leptin receptor neurons. [PDF]
Kaiser L +10 more
europepmc +1 more source
Web portal for interrogating Adverse Events of GLP‐1 RA in diabetes vs weight control/obesity. ABSTRACT Objective This study aimed to assess the spectrum and frequency of adverse events (AEs) linked to glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) using the US FDA Adverse Event Reporting System (FAERS).
David Stone +3 more
wiley +1 more source
Precision nutrition in weight loss and neuroendocrine control of people with obesity: The study protocol of a factorial randomised controlled trial (GenON Programme). [PDF]
Balbino KP +11 more
europepmc +1 more source
Antiobesity Potential of Selected Latin American Edible Plants: A Review. [PDF]
Hernández-Pérez T, Paredes-López O.
europepmc +1 more source
Metabolic aspects of satiety [PDF]
openaire +2 more sources
Effectiveness and Safety of Setmelanotide in a Patient With a Heterozygous PCSK1 Deficiency
ABSTRACT Setmelanotide, a melanocortin 4 receptor (MC4R) agonist, is a promising pharmacological treatment option for people with rare monogenic obesity conditions affecting the leptin‐melanocortin signaling pathway, including proprotein convertase subtilisin/kexin type 1 (PCSK1) gene mutations.
Ellina Lytvyak +2 more
wiley +1 more source
Associations between Eating Behaviours and Psychological Characteristics with Body Mass Index Change and Appetite-Related Changes during Incretin-Based Therapy. [PDF]
Kapan A +4 more
europepmc +1 more source
ABSTRACT Objective We examined whether genetic risk for higher BMI, parental feeding practices (restriction, pressure to eat, and monitoring), and their interactions were associated with overweight trajectories during adolescence. Methods Data came from 5568 participants aged 10–18 in the Twins' Early Development Study who had at least one measurement ...
Marthe de Roo +4 more
wiley +1 more source
Post-sleeve gastrectomy weight loss: Role of botulinum toxin and semaglutide injections. [PDF]
Li Z +11 more
europepmc +1 more source

