Results 61 to 70 of about 648,927 (269)
SPG4 and Dementia: Expanding the Clinical Spectrum
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza +19 more
wiley +1 more source
Education SciencesHigher education is key to developing a competent and engaged society. Therefore, holistic learning is a fundamental element. This study aimed to test the validity and reliability of a questionnaire for extracurricular teaching actions in higher ...
Irene Soto-Fernández +10 more
doaj +1 more source
Measuring dimensions of service quality [PDF]
Strategic Management, 2020 In the modern business environment, service companies face the challenge of continuous improvement of the quality of services. Retail managers must use an adequate system for evaluating the quality of the services they provide within the retail ...
Tešić Dejan
doaj
Safety and Tolerability of Givinostat: Evidence From Real‐World and Clinical Practice
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective The aim of our study was to establish the prevalence of adverse events in a real‐world setting in boys living with Duchenne muscular dystrophy (DMD) treated with givinostat as part of an Expanded Access Program (EAP) in Italy. Methods The cohort included 90 ambulant boys, with age when treatment started between 6 and 23 years (mean ...
Marika Pane +19 more
wiley +1 more source
Türk Spor ve Egzersiz Dergisi, 2018 While consumer motivation is considered as a theoretical approach that explains how individuals choose to engage in various consumption behaviors at certain times, the theory of disapproval provides a common theoretical basis for exploring and explaining
Oğuhan Demirhan, Ersin Eskiler
doaj +1 more source
Subjective well-being and place loyalty in Rural areas [PDF]
فصلنامه رفاه اجتماعی, 2023 Introduction: Subjective well-being is the subjective component of quality of life. People with higher subjective well-being are expected to feel a good sense toward their surrounding environment, especially their residence place.
Ramin Alborzi +2 more
doaj
Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin +11 more
wiley +1 more source
Backdoors to Satisfaction [PDF]
, 2012 A backdoor set is a set of variables of a propositional formula such that fixing the truth values of the variables in the backdoor set moves the formula into some polynomial-time decidable class. If we know a small backdoor set we can reduce the question of whether the given formula is satisfiable to the same question for one or several easy formulas ...
Serge Gaspers, Stefan Szeider
openaire +2 more sources
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller +14 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers +19 more
wiley +1 more source