Results 31 to 40 of about 1,473 (264)

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

Passively Q-Switched Thulium-Doped Fiber Laser Employing a Glycerin-Based Saturable Absorber

open access: yesFibers
A passively Q-switched Thulium-doped fiber laser based on glycerin as the saturable absorber is experimentally demonstrated for the first time. The saturable absorber consists of two FC/PC connectors aligned within a mechanical fiber-fiber coupler, with ...
Edwin Addiel Espinosa-De-La-Cruz   +8 more
doaj   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

open access: yesFEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar   +4 more
wiley   +1 more source

Physical vapor deposition of large-scale PbSe films and its applications in pulsed fiber lasers

open access: yesNanophotonics, 2019
Lead selenide (PbSe) is a new emerging semiconductor with layer-dependent bandgap that has attracted much interest due to its high infrared response and good environmental stability.
Gao Qun   +8 more
doaj   +1 more source

Study of a Graphene Saturable Absorber Film Fabricated by the Optical Deposition Method

open access: yesIEEE Photonics Journal, 2019
A film composed of graphene saturable absorber ($GSA$) prepared for a passive mode-locking (PML) fiber laser is successfully fabricated by an optical deposition method.
Xinyue Zhu, Shufen Chen
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Numerical analysis of molecules intersystem crossing effect on a passively Q- switched laser pulse characteristics

open access: yesIraqi Journal of Physics, 2021
The effect of molecules intersystem crossing (Kisc) on characteristics (energy and duration) of a Passive Q- switched Laser Pulse has been studied by mathematical description (rate equations model) for temporal performance of which was used as a ...
Abdul-Kareem Mahdi Salih
doaj  

Generation of Bright-Dark Soliton Pairs in Mode-Locked Fiber Laser Based on Molybdenum Diselenide

open access: yesIEEE Access, 2020
In this article, molybdenum diselenide (MoSe2) was fabricated by chemical vapor deposition (CVD) with a modulation depth of about 7.3% and nonsaturable loss of about 30.6%.
Xiaofa Wang, Huihui Han, Dongxin Liu
doaj   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

open access: yesFEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose   +9 more
wiley   +1 more source

All-fibre mode-locked laser using SMF-GIMF-SMF structure as artificial saturable absorber

open access: yesResults in Optics
In this work, we proposed and experimentally demonstrated a combination of single mode fibre (SMF) with graded indexed multimode fibre (GIMF) to form an artificial saturable absorber. A SMF-GIMF-SMF structure is incorporated into Erbium-doped fibre laser
Yu Chen   +5 more
doaj   +1 more source

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