Results 141 to 150 of about 1,037,660 (307)
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw +5 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit +11 more
wiley +1 more source
Soil carbon saturation : evaluation and corroboration by long-term incubations
, 2008 Although current assessments of agricultural management practices on soil organic C (SOC) dynamics are usually conducted without any explicit consideration of limits to soil C storage, it has been hypothesized that the SOC pool has an upper, or ...
Conant, Richard T. +4 more
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers +19 more
wiley +1 more source
On the Nuclear Saturation [PDF]
Progress of Theoretical Physics, 1953 Ogawa, Syûzô, Marumori, Toshio
openaire +1 more source
T1 Over Squared Proton Density Ratio to Characterize Multiple Sclerosis Lesions
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Differentiating remyelinated from demyelinated lesions in MS remains challenging without histological confirmation. This study introduces the T1‐to‐PD2 ratio (TPR) imaging approach and evaluates its ability to characterize MS lesions alongside other quantitative MRI (qMRI) metrics. Methods Thirty individuals with MS (mean age: 47.5 ±
Sarah J. Wright +10 more
wiley +1 more source
Analyse dynamique des générateurs éoliens lors d’un creux de tension du réseau
Revue des Énergies Renouvelables, 2009 Le générateur asynchrone est de plus en plus utilisé dans les systèmes de production éoliens. Le générateur asynchrone à double alimentation est le mieux adapté pour les systèmes éoliens comparativement au générateur autonome qui sert à alimenter des ...
S. Mekhtoub, R. Ibtiouen, S. Bacha
doaj
Ponderomotive saturation of magnetospheric field line resonances
, 1995 Compressional Alfvén waves in the terrestrial magnetospheric cavity constitute a discrete spectrum of global modes which can resonate with specific components of the continuum spectrum of shear Alfvén wave (SAW) field line resonant frequencies.
Rankin, Robert +3 more
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To determine whether myelin‐sensitive quantitative MRI reveals microstructural abnormalities in normal‐appearing cortex (NACtx) in myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), indicating that conventional MRI underestimates remission residual cortical injury.
Valentina Camera +20 more
wiley +1 more source
Hypergraph Saturation Irregularities
The Electronic Journal of Combinatorics, 2018 Let $\mathcal{F}$ be a family of $r$-graphs. An $r$-graph $G$ is called $\mathcal{F}$-saturated if it does not contain any members of $\mathcal{F}$ but adding any edge creates a copy of some $r$-graph in $\mathcal{F}$. The saturation number $\operatorname{sat}(\mathcal{F},n)$ is the minimum number of edges in an $\mathcal{F}$-saturated graph on $n ...
openaire +3 more sources