Results 51 to 60 of about 695,635 (268)

Benchmarking of Sensor Configurations and Measurement Sites for Out-of-the-Lab Photoplethysmography

open access: yesSensors, 2023
Photoplethysmography (PPG) is used for heart-rate monitoring in a variety of contexts and applications due to its versatility and simplicity. These applications, namely studies involving PPG data acquisition during day-to-day activities, require reliable
Max Nobre Supelnic   +4 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Induction in Saturation

open access: yes
Abstract Proof by induction is commonplace in modern mathematics and computational logic. This paper overviews and discusses our recent results in turning saturation-based first-order theorem proving into a powerful framework for automating inductive reasoning.
Laura Kovács   +3 more
openaire   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Automorphisms of Saturated and Boundedly Saturated Models of Arithmetic

open access: yesNotre Dame Journal of Formal Logic, 2011
We discuss automorphisms of saturated models of PA and boundedly saturated models of PA. We show that Smorynski's Lemma and Kaye's Theorem are not only true for countable recursively saturated models of PA but also true for all boundedly saturated models of PA with slight modifications.
Nurkhaidarov, Ermek S., Shochat, Erez
openaire   +2 more sources

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Deuterium retention in recrystallized tungsten exposed to high-flux plasma with fluences up to 1 × 1029 m−2

open access: yesNuclear Fusion
Plasma fluence at the divertor of a future magnetic confinement fusion device can accumulate up to ∼10 ^28 –10 ^29 m ^−2 per year. Yet hydrogen isotope (HI) retention under such high-fluence plasma exposure has been rarely reported.
Yi-Wen Sun   +10 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Macro-micro mechanical behavior research on gas hydrate bearing coal based on parallel bonding model

open access: yesMeitan xuebao
Discrete element simulation of triaxial compression test was carried out to study the effects of confining pressure and saturation on the macro and meso mechanical properties of gas hydrate bearing coal (GHBC).
Nannan WANG   +4 more
doaj   +1 more source

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