Results 61 to 70 of about 174,047 (268)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Interest Rate-Savings Nexus: Keynesian-Classical Debate Revisiting in OECD Economies

İktisat Politikası Araştırmaları Dergisi
There are many factors that determine savings, especially income and consumption. However, classical and Keynesian economic theories disagree on how interest rates affect savings. According to classical theory, an increase in interest rates will increase
Abdullah Miraç Bükey
doaj   +1 more source

Different mechanisms contributing to savings and anterograde interference are impaired in Parkinson’s disease

Frontiers in Human Neuroscience, 2013
Reinforcement and use-dependent plasticity mechanisms have been proposed to be involved in both savings and anterograde interference in adaptation to a visuomotor rotation (c.f.Huang et al., 2011).
Li-Ann eLeow, Li-Ann eLeow, Aymar ede Rugy, Andrea Mary Loftus, Andrea Mary Loftus, Geoff eHammond   +5 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

The impact of social media on fund net capital flow and performance

Humanities & Social Sciences Communications
Numerous market phenomena show that social media can have an impact on investor behavior, but there is a lack of exploration in existing literature regarding the impact mechanism of social media on fund investment behavior and performance.
Caiming Nie, Yang Gao, Ting Ren
doaj   +1 more source

The effects of financial literacy and materialism on the savings decision of generation Z Indonesians

Cogent Business & Management, 2020
The purpose of this research is to analyze the influence of financial literacy and materialism on the savings decision of Indonesia’s generation Z.
Stevanus Pangestu, Erwin Bramana Karnadi
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Potential shared mechanisms in atopic dermatitis and type 2 diabetes identified via transcriptomic and machine learning approaches

Scientific Reports
Although atopic dermatitis (AD) and type 2 diabetes mellitus (T2DM) may appear clinically and pathophysiologically unrelated, AD is a common skin disease characterized by chronic inflammation and skin barrier dysfunction, whereas T2DM is a metabolic ...
Yang Zhang, Qiangman Wei, Qianzhi Chen
doaj   +1 more source

Tempo de permanência de enfermeiros em um hospital-escola e valores monetários despendidos nos processos de admissão, desligamento e provimento de novo profissional Tiempo de permanencia de enfermeras en un hospital-escuela y su relación con el monto gasto en la admisión, salida y provisión de nuevo profesional Time of permanence of nurses at a school-hospital and expenses related to admission, resignation and hiring of a new professional

Revista Latino-Americana de Enfermagem, 2005
Este estudo descritivo teve como objetivo conhecer o tempo de permanência dos enfermeiros numa instituição hospitalar e sua relação com o valor monetário em horas/salário, referente à admissão, à saída e ao provimento de novo enfermeiro. Foram analisados
Flávia Lilalva de Holanda, Isabel Cristina Kowal Olm Cunha   +1 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source