Results 51 to 60 of about 59,411 (181)

Senior Programmers: Characteristics of Elderly Users from Stack Overflow

open access: yes, 2017
In this paper we presents results of research about elderly users of Stack Overflow (Question and Answer portal for programmers). They have different roles, different main activities and different habits.
A Dickinson   +11 more
core   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

open access: yesMolecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande   +11 more
wiley   +1 more source

The digital-only media consumer: Key findings from a conversation with all-digital millenials [PDF]

open access: yes
This study offers insight on the digital-onlys, a sub-population of Millennials who only consume media through digital platforms. Based on informal group conversations with 16 to 34 year-olds, the study provides a snapshot of their daily media ...
Danielle Desjardins
core  

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

FOTE 2008 Conference Report [PDF]

open access: yes, 2008
A report prepared by JA.Net and ULCC about the Future of Technology in Education (FOTE 2008) conference, Imperial College, 3rd October 2008. It covers the main speakers, themes and presentations: Cloud Computing, Second Life, Portability, Personalisation,
Bush, Tim
core  

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

The new frontier: Singaporean and Malaysian public relations practitioners’ perceptions of new media [PDF]

open access: yes, 2009
Recent research into social media use identified mid-2006 to early 2007 as the period when Singaporean public relations agencies first recognised the need to embrace new media (Fitch, 2009a).
Fitch, K.
core   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Factors Influencing Adoption of Remotely Sensed Imagery for Site-Specific Management in Cotton Production [PDF]

open access: yes
This research evaluated the factors that influenced cotton producers to adopt remote sensing for variable rate application of inputs. Farmers who were younger, more highly educated, had a larger farm operation, and were more technologically savvy were ...
English, Burton C.   +7 more
core   +1 more source

The Democratization of Data in Higher Education: A Case Study of the Challenges that Institutions Face as They Seek to Improve Student Success [PDF]

open access: yes, 2004
In the current climate of increased external accountability and increased internal pressure to improve student performance, many colleges and universities are grappling with how to broaden access to data and information so as to improve decision-making --
Lisa Petrides
core  

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