Results 41 to 50 of about 3,450,723 (274)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Multi-Attribute Decision-Making Methods as a Part of Mathematical Optimization

open access: yesMathematics, 2019
Optimization problems are relevant to various areas of human activity. In different cases, the problems are solved by applying appropriate optimization methods. A range of optimization problems has resulted in a number of different methods and algorithms
Irina Vinogradova
doaj   +1 more source

PENERAPAN MADM DENGAN METODE SAW UNTUK MENENTUKAN TARGET PROMOSI BERDASARKAN ASAL JURUSAN DI SEKOLAH

open access: yesSimetris: Jurnal Teknik Mesin, Elektro dan Ilmu Komputer, 2021
Penerimaan Mahasiswa Baru (PMB) adalah proses yang sangat penting untuk merekrut mahasiswa baru, di mana jumlah mahasiswa sangat penting untuk operasional dan perencanaan pengembangan Perguruan Tinggi Swasta (PTS).
B. T. SUTRISNO, Widyastuti Andriyani
doaj   +1 more source

Saw-tooth cardiomyopathy [PDF]

open access: yesJournal of Cardiovascular Magnetic Resonance, 2009
We present an unusual case of cardiomyopathy in a two month old male infant with a grade-I systolic murmur. Echocardiographic examination disclosed left ventricular (LV), dysplasia with saw-tooth like inwards myocardial projections extending from the lateral walls towards the LV cavity.
Karatza Ageliki A   +4 more
openaire   +3 more sources

Field experience with various slicing methods [PDF]

open access: yes, 1982
Wafer slicing using internal diameter (ID) saw, multiblade slurry (MBS) saw and multiwire slurry (MWS) saw techniques were evaluated. Wafer parameters such as bow, taper, and roughness which may not be important factors for solar cell fabrication, were ...
Yoo, H. I.
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Más allá del desagüe: priorización de zonas agrícolas aptas para reutilización de aguas residuales mediante SIG y análisis multicriterio

open access: yesIngeniería del Agua
Ante la situación de estrés hídrico global y la creciente demanda de agua, se vuelve fundamental promover la revalorización de fuentes alternativas como las aguas residuales regeneradas.
Irene Ochoa, Daniel Jato-Espino
doaj   +1 more source

See-saw and grand unification

open access: yes, 2005
I review the profound connection between the see-saw mechanism for neutrino masses and grand unification. This connection points naturally towards SO(10) grand unified theory.
Senjanovic, Goran
core   +1 more source

Functional Connectivity Linked to Cognitive Recovery After Minor Stroke

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Patients with minor stroke exhibit slowed processing speed and generalized alterations in functional connectivity involving frontoparietal cortex (FPC). The pattern of connectivity evolves over time. In this study, we examine the relationship of functional connectivity patterns to cognitive performance, to determine ...
Vrishab Commuri   +7 more
wiley   +1 more source

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