Results 21 to 30 of about 448 (120)

Lysosomal Storage Disorders: Molecular Basis and Therapeutic Approaches [PDF]

open access: yes, 2022
Lysosomal storage disorders are a heterogenoeus group of rare genetic conditions affecting worldwide population and often exhibiting severe clinical manifestations.

core   +1 more source

Large-scale proteomics analysis of five brain regions from Parkinson's disease patients with a GBA1 mutation. [PDF]

open access: yesNPJ Parkinsons Dis
Despite being the second most common neurodegenerative disorder, little is known about Parkinson's disease (PD) pathogenesis. A number of genetic factors predispose towards PD, among them mutations in GBA1, which encodes the lysosomal enzyme acid-β ...
Blumenreich S   +8 more
europepmc   +3 more sources

The database of the PREDICTS (Projecting Responses of Ecological Diversity In Changing Terrestrial Systems) project

open access: yesEcology and Evolution, Volume 7, Issue 1, Page 145-188, January 2017., 2017
The collation of biodiversity datasets with broad taxonomic, biogeographic, and spatial extents is necessary to understand historical declines and to project—and hopefully avert—future declines. We describe and make freely available a database of more than 3.2 million biodiversity measurements from 94 countries representing over 47,000 species ...
Lawrence N. Hudson   +514 more
wiley   +1 more source

Flavonoid Composition and Biological Activities of Ethanol Extracts of Caryocar coriaceum Wittm., a Native Plant from Caatinga Biome

open access: yesEvidence-Based Complementary and Alternative Medicine, Volume 2017, Issue 1, 2017., 2017
Caryocar coriaceum fruits, found in Brazilian Cerrado and Caatinga, are commonly used as food and in folk medicine, as anti‐inflammatory, bactericide, fungicide, leishmanicide, and nematicide. Due to the biological potential of this plant, this study focuses on the evaluation of antifungal and antileishmanial activities, including anticholinesterase ...
Daniela Ribeiro Alves   +11 more
wiley   +1 more source

CD157 is an important mediator of neutrophil adhesion and migration [PDF]

open access: yes, 2004
CD157, a glycosylphosphatidylinositol (GPI)–anchored protein encoded by a member of the CD38 NADase/ADP-ribosyl cyclase gene family, is expressed on the surface of most human circulating neutrophils.
Ferranti, Bruna   +6 more
core   +2 more sources

The role of CD38 and TRPM2 in adipose tissue and liver during thermogenesis [PDF]

open access: yes, 2022
BACKGROUND: Different strategies to boost cellular NAD+ levels, such as supplementation of NAD+ precursors, or inhibition of NAD+ consumption, are currently under investigation as promising means to promote healthy aging and ameliorate dysfunctional ...
Benzi, Andrea
core   +1 more source

6th International Symposium on Molecular Allergology (ISMA)

open access: yesClinical and Translational Allergy, Volume 6, Issue S2, 18 October 2016., 2016
Table of contents ORAL ABSTRACTS Symposium 1: Biochemistry, structure and environment of the allergen: what makes a protein an allergen? O1 Two cell‐membrane peptidases carrying galactose‐alpha‐1,3‐galactose are implicated in delayed anaphylactic reactions upon pork kidney ingestion in patients with IgE‐antibodies to alpha‐Gal Christiane Hilger, Kyra ...
Christiane Hilger   +471 more
wiley   +1 more source

Performance of Narrowband Signal Detection under Correlated Rayleigh Fading Based on Synthetic Array

open access: yesInternational Journal of Antennas and Propagation, Volume 2009, Issue 1, 2009., 2009
The performance of a single moving antenna receiver in detecting a narrowband signal under correlated Rayleigh fading is considered. The spatial motion of the antenna during signal capture provides a realization of a synthetic antenna array. As shown, there is a net processing gain obtained by using a synthetic antenna array compared to the equivalent ...
Ali Broumandan   +3 more
wiley   +1 more source

Ribosomes as Sensors: How Cells Utilize the Translational Process to Monitor Cellular Conditions [PDF]

open access: yes, 2023
The discovery that collisions between ribosomes are the key signaling event that triggers quality control and stress response pathways in eukaryotes has changed our understanding of how cells sense and respond to the environment.
Kim, Kyusik Q
core   +2 more sources

UEG Week 2018 Poster Presentations [PDF]

open access: yesUnited European Gastroenterol J, 2018
United European Gastroenterology Journal, Volume 6, Issue S8, Page A135-A747, October 2018.
europepmc   +2 more sources

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