Results 61 to 70 of about 1,726,403 (273)

Creation of the spacecraft’s command-and-measurement system’s heterogeneous simulation model

open access: yesКосмические аппараты и технологии, 2020
This article presents software tools designed for construction of heterogeneous models by software integration of logical models having their work methods set in the knowledge bases and engineering models created in a technical simulation environment. In
O. S. Isaeva   +5 more
doaj   +1 more source

The abandoned antimony-mines of SE Sardinia: impact on surface waters [PDF]

open access: yes, 2008
This study investigates the impact of abandoned Sb-mines on the Flumendosa River, which is the most important water resource in southern Sardinia. Hydrogeochemical surveys carried out in 2005 and 2006 indicated a significant impact of waters flowing ...
BIDDAU, RICCARDO   +5 more
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Efficacy and safety of fixed-combination bimatoprost/timolol ophthalmic solution

open access: yesPatient Preference and Adherence, 2017
Suk Bae Moon,1 Sang Beom Han21Department of Surgery, Kangwon National University Hospital, Kangwon National University Graduate School of Medicine, Chuncheon, Korea, 2Department of Ophthalmology, Kangwon National University Hospital, Kangwon National ...
Moon SB, Han SB
doaj  

AN 80-YEAR-OLD WOMAN WITH LEFT SHOULDER PAIN [PDF]

open access: yesMalaysian Family Physician, 2010
This case history illustrates the real life experience and dilemma of an 80-year-old woman in pursuit of medical care for her left shoulder pain. Points for discussion range from clinical features of Pancoast tumor, importance of pain management, good ...
KHOO SB
doaj  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Variational study of J_(1)-J_(2) Heisenberg model on kagome lattice using projected Schwinger-boson wave functions [PDF]

open access: yes, 2011
Motivated by the unabating interest in the spin-1/2 Heisenberg antiferromagnetic model on the kagome lattice, we investigate the energetics of projected Schwinger-boson (SB) wave functions in the J_(1)-J_(2) model with antiferromagnetic J_(2) coupling ...
Motrunich, Olexei I., Tay, Tiamhock
core  

The effect of nearest neighbor spin-singlet correlations in conventional graphene SNS Josephson junctions

open access: yes, 2009
Using the self-consistent tight-binding Bogoliubov-de Gennes formalism we have studied the effect of nearest neighbor spin-singlet bond (SB) correlations on Josephson coupling and proximity effect in graphene SNS Josephson junctions with conventional s ...
Annica M. Black-Schaffer   +3 more
core   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

open access: yesFEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl   +13 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

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