Results 61 to 70 of about 107,776 (244)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Damping Behavior of the Phenolic Based Composite Friction Materials Containing Thermoplastic Elastomers (TPEs) [PDF]

Iranian Journal of Chemistry & Chemical Engineering, 2006
Attempts have been made for the first time to produce a friction material with thermal sensitive modulus by the inclusion of combined plastic/rubber properties of thermoplastic elastomers (TPE) as viscoelastic polymeric materials into the formulation for
Mohsen Masoomi, Ali Asghar Katbab, Hossein Nazockdast   +2 more
doaj  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Learning-Based Optimization of Cache Content in a Small Cell Base Station

, 2014
Optimal cache content placement in a wireless small cell base station (sBS) with limited backhaul capacity is studied. The sBS has a large cache memory and provides content-level selective offloading by delivering high data rate contents to users in its ...
Blasco, Pol, Gunduz, Deniz
core   +1 more source

A Keck Survey of Gravitational Lens Systems: I. Spectroscopy of SBS 0909+532, HST 1411+5211, and CLASS B2319+051 [PDF]

, 1999
We present new results from a continuing Keck program to study gravitational lens systems. We have obtained redshifts for three lens systems, SBS 0909+532, HST 1411+5211, and CLASS B2319+051.
A. C. S. Readhead, Angonin-Willaime M.-C., C. D. Fassnacht, Engels D., Jackson N., L. M. Lubin, Poggianti B. M., R. D. Blandford, Refsdal S., Stepanyan D. A., T. Kundić, Thimm G. J., van der Marel R. P.   +12 more
core   +4 more sources

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Evaluating Shear Bond Strength of Different Glass Ionomer Cements to Dentin: An Experimental Study

Journal of Pharmacy and Bioallied Sciences
Aim: The study aimed to estimate the shear bond strength (SBS) of various glass ionomer cements (GICs). Materials and Methods: Forty-eight extracted premolars were divided into 12 each groups after doing coronal sectioning 1 mm under the junction of ...
Sulakshana Pradeep, Gunmeek Kaur, Bhaswati Roy, Dhaval Desai, MR Athira, K Vishnu Prasad, Hiren Hansraj Paradiya   +6 more
doaj   +1 more source

Searching for Diffuse Nonthermal X-Rays from the Superbubbles N11 and N51D in the Large Magellanic Cloud

, 2010
We report on observations of the superbubbles (SBs) N11 and N51D in the Large Magellanic Cloud (LMC) with Suzaku and XMM-Newton. The interior of both SBs exhibits diffuse X-ray emission, which is well represented by thin thermal plasma models with a ...
A. Bamba, Bamba, Bomans, Butt, Bykov, Cooper, Dunne, Ezoe, Fujita, H. Yamaguchi, Hatano, Hughes, Koyama, M. Sawada, Mac Low, Maddox, Mitsuda, Muno, Oey, Persson, Serlemitsos, Smith, Tawa, Tsujimoto, Walborn, Wolk, Yamaguchi   +26 more
core   +1 more source

Helium abundance in the most metal-deficient blue compact galaxies: I Zw 18 and SBS 0335-052 [PDF]

, 1999
We present high-quality spectroscopic observations of the two most-metal deficient blue compact galaxies known, I Zw 18 and SBS 0335-052 to determine the helium abundance.
Bonifacio P., Brocklehurst M., Campbell A., Caso C., Craig B. Foltz, Frederic H. Chaffee, Jaschek M., Legrand F., Leone F., Maeder A., Melnick J., Natalia G. Guseva, Olofsson K., Pagel B. E. J., Papaderos P., Peimbert M., Richard F. Green, Smits D. P., Stasinska G., Trinh X. Thuan, Vilchez J. M., Yuri I. Izotov   +21 more
core   +2 more sources

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source