Results 51 to 60 of about 6,394,366 (198)

BIOCHEMICAL, IMMUNOLOGICAL AND HISTOPATHOLOGICAL STUDIESON THE EFFECT OF SACCHAROMYCES CEREVISIAEIN RABBITS EXPOSED TOAFLATOXIN B1 [PDF]

Assiut Veterinary Medical Journal, 2014
The purpose of this study aimed to investigate the influence of different doses of probiotic (Saccharomyces cerevisiae) co-administrated with Aflatoxin B1 in male rabbits and study the possible protection against its adverse effect.
ABEER, M. ANWER, ABEER, E. EL-METWALLY, MAHA IBRAHIM   +2 more
doaj   +1 more source

Efficacy, pharmacokinetics, and safety of subcutaneous C1-esterase inhibitor as prophylaxis in Japanese patients with hereditary angioedema: Results of a Phase 3 study

Allergology International, 2023
Background: Hereditary angioedema (HAE) is a rare and potentially life-threatening genetic disorder characterized by recurrent attacks of angioedema. HAE types I and II result from deficient or dysfunctional C1-esterase inhibitor (C1–INH).
Tomoo Fukuda, Keiko Yamagami, Kimito Kawahata, Yuzo Suzuki, Yoshihiro Sasaki, Takashi Miyagi, Iris Jacobs, John-Philip Lawo, Fiona Glassman, Hideto Akama, Michihiro Hide, Isao Ohsawa   +11 more
doaj   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

FEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda, Sreerama Chaitanya Sridhara, Aura Carreira   +2 more
wiley   +1 more source

Cross-section measurement of ⁴⁴Sc, ⁴⁷Sc, ⁴⁸Sc and ⁴⁷Ca for an optimized ⁴⁷Sc production with an 18 MeV medical PET cyclotron [PDF]

, 2019
Novel medical radioisotopes for both diagnostic and therapy are essential for the future development of personalized nuclear medicine. Among them, radiometals can be used to label both proteins and peptides and encompass promising theranostic pairs.
Carzaniga, Tommaso Stefano, Braccini, Saverio, Carzaniga TS, Braccini S   +3 more
core   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Uso de sensoriamento remoto para análise ambiental do Parque Manguezal do Itacorubi, Florianópolis - SC [PDF]

, 2000
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico.Entre as paisagens que aprensentam maior fragilidade na sua relação com o homem, os manguezais recebem impactos consideráveis, especialmente pela sua localização em ...
Bernardy, Rógis Juarez
core  

Studies on hyperfine structure of Sc I and Sc II using Fourier-transform spectroscopy

, 2021
New magnetic dipole hyperfine structure (HFS) constants A of Sc I and Sc II were derived by analyzing of the transition lines ranging from 3998 to 39,979 $$\hbox {cm}^{-1}$$ in the Fourier-transform (FT) spectra which was recorded in the US National ...
Yixin Xu, Meina Liu, Yang Yang, Huiting Ma, Hui Fu, Die Fang, Zhihu Yang, Zhenwen Dai   +7 more
core   +1 more source

Fiber Type-Specific Satellite Cell Content in Cyclists Following Heavy Training With Carbohydrate and Carbohydrate-Protein Supplementation

Frontiers in Physiology, 2016
The central purpose of this study was to evaluate the fiber type-specific satellite cell and myonuclear responses of endurance-trained cyclists to a block of intensified training, when supplementing with carbohydrate (CHO) vs. carbohydrate-protein (PRO).
Alec I McKenzie, Andrew C D'Lugos, Michael J Saunders, Keith D Gworek, Nicholas D Luden   +4 more
doaj   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source