Mucuna pruriens (Velvet bean) Rescues Motor, Olfactory, Mitochondrial and Synaptic Impairment in PINK1(B9) Drosophila melanogaster Genetic Model of Parkinson's Disease [PDF]
The fruit fly Drosophila melanogaster (Dm) mutant for PTEN-induced putative kinase 1 (PINK1B9) gene is a powerful tool to investigate physiopathology of Parkinson's disease (PD). Using PINK1B9 mutant Dm we sought to explore the effects of Mucuna pruriens
Acquas E +14 more
core +1 more source
Spirotetramat reduces fitness of the spotted‐wing Drosophila, Drosophila suzukii
Oral take up of spirotetramat by Drosophila suzukii females inhibits the activity of acetyl‐CoA decarboxylase (ACC) that is needed for fecundity and desiccation resitance. Abstract With climate change, the spotted‐wing Drosophila (SWD, Drosophila suzukii) invades a great number of fruit production regions worldwide. A plethora of insecticides are being
Jing Yang +3 more
wiley +1 more source
Field Investigation of Controlled Sediment Flushing at Sernio Pondage [PDF]
6Sernio barrage (central Italian Alps) dams the Adda river 75 km above its mouth in lake Como. The project diverts water to a run-of-the-river hydropower plant (30 MW installed capacity, 40 m3/s rated discharge).
core
A plant natriuretic peptide-like molecule of the pathogen Xanthomonas axonopodis pv. citri causes rapid changes in the proteome of its citrus host [PDF]
Background Plant natriuretic peptides (PNPs) belong to a novel class of peptidic signaling molecules that share some structural similarity to the N-terminal domain of expansins and affect physiological processes such as water and ion homeostasis at nano ...
Betiana S Garavaglia +8 more
core +2 more sources
Abstract Aim Species responses to global warming will depend on intraspecific diversity, yet studies of factors governing biogeographic patterns of variability are scarce. Here, we investigate the evolutionary processes underlying genetic and phenotypic diversity in the flightless and cold‐adapted grasshopper Sigaus piliferus, and project its suitable ...
Fabio Leonardo Meza‐Joya +2 more
wiley +1 more source
Pyridazine-bridged cationic diiridium complexes as potential dual-mode bioimaging probes [PDF]
A novel diiridium complex [(N^C^N)2Ir(bis-N^C)Ir(N^C^N)2Cl]PF6 (N^C^N = 2-[3-tert-butyl-5-(pyridin-2-yl)phenyl]pyridine; bis-N^C = 3,6-bis(4-tert-butylphenyl)pyridazine) was designed, synthesised and characterised.
Bryant, H.E. +5 more
core +2 more sources
Bacterial and mammalian cells are rich in putrescine, spermidine, and spermine. Polyamines are required for optimum fitness, but the biological function of these small aliphatic compounds has only been partially revealed. Known functions of polyamines include interaction with nucleic acids that alters gene expression and with proteins that modulate ...
Lawrence M. Schopfer +4 more
wiley +1 more source
Cardiorespiratory physiology and swimming energetics of a high-energy-demand teleost, the yellowtail kingfish (Seriola lalandi) [PDF]
This study utilizes a swimming respirometer to investigate the effects of exercise and temperature on cardiorespiratory function of an active teleost, the yellowtail kingfish (Seriola lalandi). The standard aerobic metabolic rate (SMR) of S.
Clark, T., Seymour, R.
core +1 more source
Proline-Rich Homeodomain protein (PRH/HHEX) is a suppressor of breast tumour growth [PDF]
Breast tumours progress from hyperplasia to ductal carcinoma in situ (DCIS) and invasive breast carcinoma (IBC). PRH/HHEX (Proline Rich Homeodomain/Haematopoietically expressed homeobox) is a transcription factor that displays both tumour suppressor and ...
Bicknell, Roy +9 more
core +4 more sources
The molecular basis for apolipoprotein E4 as the major risk factor for late onset Alzheimer's disease [PDF]
Apolipoprotein E4 (ApoE4) is one of three (E2, E3 and E4) human isoforms of an -helical, 299-amino acid protein. Homozygosity for the ε4 allele is the major risk factor for developing late onset Alzheimer’s disease (AD).
Al-Hilaly, Youssra +6 more
core +5 more sources

