Results 151 to 160 of about 53,028 (278)

Recent Advances in Top‐Down Proteomics for Single‐Cell Research

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Individual cells have distinctive molecular characteristics, including biologically relevant proteoforms. Although single‐cell (SC) molecular omics offer unprecedented insights into cellular heterogeneity and function, the characterization of proteoforms in SCs remains an uncharted territory.
Jake A. Melby, Pei Su, Fabio P. Gomes
wiley   +1 more source

Efficient FPGA implementation of polar codes-based information reconciliation for quantum key distribution. [PDF]

Sci Rep
Liao L, Wu X, Chen Y, Fan X, Tian Z, Huang J, Mu T, Guo J, Liu M, Liu B, Sun S.   +10 more
europepmc   +1 more source

Advances in GPCRs Associated With Wnt Signaling Within the Auditory System

Medicine Bulletin, EarlyView.
ABSTRACT G protein‐coupled receptors (GPCRs) that interact with the Wnt signaling pathway are pivotal for auditory system homeostasis, as they orchestrate inner ear development, hair cell (HC) regeneration, and hearing preservation. Frizzled (FZD) receptors, the core Wnt‐related GPCRs, bind Wnt ligands and co‐receptors (e.g., LRP5/6) to activate both ...
Liang Wang, Changling Xu, Jiangang Fan, Renjie Chai   +3 more
wiley   +1 more source

CMAISE: Establishing the Longitudinal Multi‐Omics Cohort for Sepsis Precision Medicine

Med Research, EarlyView.
ABSTRACT Sepsis remains a leading cause of mortality worldwide due to its profound biological heterogeneity. While multi‐omics approaches offer promise for precision medicine, existing datasets often lack longitudinal granularity or comprehensive clinical integration. We present the Chinese Multi‐omics Advances In Sepsis (CMAISE) cohort, a prospective,
Jie Yang, Suibi Yang, Jiajun Cai, Songzan Qian, Shuping Song, Jun Guo, Yang Wang, Jinyan Xing, Bo Zhang, Zhihao Wang, Shengze Wu, Xinhao Jin, Bowen Tan, Dongdong Yang, Yao Yan, Haoran Chen, Changlin Sun, Kang Zou, Yuxin Leng, Jingye Pan, Tianlong Zhang, Yiming Shao, Lina Xian, Hongjun Kang, Zhen Wang, Ruilan Wang, Nan Wang, Lvyin Yan, Kun Cheng, Songqiao Liu, Lin Chen, Caibao Hu, Fuhong Su, Qian Gao, Yi Yang, Zhongheng Zhang, On behalf of Chinese Multi‐omics Advances In Sepsis (CMAISE) Consortium   +36 more
wiley   +1 more source

Polar Coding and Early SIC Decoding for Uplink Heterogeneous NOMA. [PDF]

Entropy (Basel)
Wu CJ, Lin CY, Huang YC.
europepmc   +1 more source

Diabetic Peripheral Neuropathy: Molecular Staging, Risk Factors, Therapeutics, and Emerging Trends

Med Research, EarlyView.
The heterogeneous landscape of DPN can be unified through a tripartite pathogenic model encompassing progressive stages of metabolic dysregulation, chronic inflammation, and overt neuronal damage. Within this framework, six clinical subtypes were identified, namely, hyperglycemia‐driven, dyslipidemia‐driven, inflammation‐driven, dysvascularity‐driven ...
Xiaofeng Dai, Mingze Tang
wiley   +1 more source

Shared and Unique Connectivity Signatures of Reading and Language Deficits. [PDF]

J Cogn Neurosci
Daucourt MC, Rosenblatt M, Frijters JC, Bosson-Heenan JM, Gruen JR, Scheinost D.   +5 more
europepmc   +1 more source

Inflammation, Immunity, and Cardiovascular Diseases

Med Research, EarlyView.
Cardiovascular stress signals (e.g., hemodynamic shear, oxidized lipids, and ischemia) act on endothelial and immune cells to activate and amplify inflammation through NF‐κB, the NLRP3 inflammasome, and JAK/STAT signaling, inducing proinflammatory cytokines/chemokines (IL‐6, IL‐1β, TNF‐α, and CCL2) and self‐amplifying circuits; clinically, inflammatory
Dezhi Guo, Yan Liao, Rui Zhao, Zhaoyu Li, Kaikai Wang, Haoling Zhang, Pingxin Sun, Yadong Guo, Wangzheqi Zhang   +8 more
wiley   +1 more source

Spatially global effects of feature-based attention in functional subdivisions of human subcortical nuclei. [PDF]

Commun Biol
Lin W, Qian C, Zhang YY, Liu S, Zhang X, Fang F, Zhang P.   +6 more
europepmc   +1 more source

Wall‐to‐wall Amazon forest height mapping with Planet NICFI, Aerial LiDAR, and a U‐Net regression model

Remote Sensing in Ecology and Conservation, EarlyView.
Tree canopy height is a key indicator of forest biomass and structure, yet accurate mapping across the Amazon remains challenging. Here, we generated a canopy height map of the Amazon forest at ~4.8 m resolution using Planet NICFI imagery and a deep learning U‐Net model trained with airborne LiDAR data.
Fabien H. Wagner, Ricardo Dalagnol, Griffin Carter, Mayumi C. M. Hirye, Shivraj Gill, Le Bienfaiteur Sagang Takougoum, Samuel Favrichon, Michael Keller, Jean P. H. B. Ometto, Lorena Alves, Cynthia Creze, Stephanie P. George‐Chacon, Shuang Li, Zhihua Liu, Adugna Mullissa, Yan Yang, Erone G. Santos, Sarah R. Worden, Martin Brandt, Philippe Ciais, Stephen C. Hagen, Sassan Saatchi   +21 more
wiley   +1 more source