Results 151 to 160 of about 613,611 (237)

Metrnβ drives sepsis immunosuppression via macrophage reprogramming: A novel prognostic biomarker and therapeutic target

Interdisciplinary Medicine, EarlyView.
Metrnβ serves as a novel prognostic biomarker for sepsis and that targeted blockade of the Metrnβ‐c‐Kit axis represents a promising therapeutic strategy for sepsis. Abstract Sepsis is a heterogeneous syndrome critically driven by immunosuppression, yet lacking personalized prognostic markers and therapeutic targets. Here, we provide evidence to support
Xiao Li, Ai Chen, Chen Zhang, Meihong Da, Yonghui Liu, Zhi He, Chenyan Yuan, Shuo Ma, Yuming Yao, Dawen Chen, Meiling Zhou, Zhixin Song, Wenjing Lu, Chun‐Kwok Wong, Guoqiu Wu, Xun Gao   +15 more
wiley   +1 more source

Charting higher-order models of brain function beyond pairwise interactions. [PDF]

Nat Commun
Santoro A, Neri M, Poetto S, Orsenigo D, Diano M, Gatica M, Petri G.   +6 more
europepmc   +1 more source

Improving Daily Rainfall Downscaling Over Taiwan's Complex Terrain With Surface‐Wind‐Informed Deep Learning Model

International Journal of Climatology, EarlyView.
An encoder–decoder architecture (EDA) dynamically downscales coarse‐resolution climate fields (0.25°) to high‐resolution outputs (0.05°) over Taiwan, improving the representation of fine‐scale spatial variability and localized extremes by incorporating both rainfall and surface winds to maintain physical consistency.
Yi‐Chi Wang, Chia‐Hao Chiang, Chiung‐Jui Su, Ko‐Chih Wang, Wan‐Ling Tseng, Hsin‐Chien Liang   +5 more
wiley   +1 more source

Polar Codes for Decomposed Multi-Input Multi-Output Gaussian Broadcast Channels. [PDF]

Entropy (Basel)
Şener MY, Kramer G, Shamai Shitz S, Böhnke R, Xu W.   +4 more
europepmc   +1 more source

Mechanism of Combined Improvement of Saline‐Alkali Soil by Artificial Humic Acid and Microbial Inoculant

Land Degradation &Development, EarlyView.
ABSTRACT To address the widespread constraints imposed by saline‐alkaline soils on agricultural production worldwide, the combined reclamation and carbon cycle regulation effects of artificial humic acid (AHA) and a multifunctional microbial inoculant were evaluated through pot experiments. Results demonstrated that co‐application of AHA (4 g·kg−1) and
Ying Zhao, Rui Zhang, Zeyu Zhang, Fan Yang, Zhuqing Liu   +4 more
wiley   +1 more source

Attention-related modulation in the superior colliculus encodes perceptual sensitivity, but not perceptual choice. [PDF]

Nat Commun
Ghosh S, Maunsell JHR.
europepmc   +1 more source

Interleaved Diffractive Networks for Information Transfer Through Random Diffusers

Laser &Photonics Reviews, EarlyView.
This work presents a cascaded diffractive optical network that enables information transfer through random, unknown diffusers using passive, interleaved structured layers that mitigate scattering without digital computation. A hybrid optical‐digital version further improves robustness and reconstruction fidelity under distortions, with both simulations
Yuhang Li, Yiyang Wu, Shiqi Chen, Xilin Yang, Aydogan Ozcan   +4 more
wiley   +1 more source

Recent Advances in Top‐Down Proteomics for Single‐Cell Research

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Individual cells have distinctive molecular characteristics, including biologically relevant proteoforms. Although single‐cell (SC) molecular omics offer unprecedented insights into cellular heterogeneity and function, the characterization of proteoforms in SCs remains an uncharted territory.
Jake A. Melby, Pei Su, Fabio P. Gomes
wiley   +1 more source

Active sensing during a visual perceptual decision-making task. [PDF]

iScience
Ghani N, Yang AY, International Brain Laboratory.   +2 more
europepmc   +1 more source

ChatBiobank: An AI‐Assisted Guidance Tool for Multi‐Omics Biobanking

Med Research, EarlyView.
ABSTRACT Omics‐based technologies have greatly advanced precision medicine, which relies on high‐quality biobanks to meet technical requirements. However, existing standards and technical resources address different components of biobanking, whereas integrated operational guidance connecting assay‐specific requirements, multimodal biospecimens ...
Zhao Sun, Xuejiao Xia, Rui Deng, Chang Sun, Yunfei Wang, Zhuohang Li, Jiahui Li, Guanghui Li, Mingliang Yuan, Sanfei Peng, Xiangyang Yin, Zhiwei Zhao, Xinhua Dong, Qi Liu, Jing‐Hua Yang, Zhen Yang, Yang Fu   +16 more
wiley   +1 more source