Results 131 to 140 of about 282,346 (273)

The Immunoregulatory and Hematopoietic Effects of Momelotinib in a Murine Bone Marrow Failure Model

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
Momelotinib, a selective small‐molecule inhibitor of JAK1/2 and the bone morphogenic protein receptor kinase activin A receptor type I (ACVR1), exerts its effects by inhibiting the overactivation of the BMP/ACVR1/SMAD signaling pathway. This inhibition reduces hepcidin production in hepatocytes, and reduces inflammation, aberrant cytokine signaling ...
Yue Zhang   +7 more
wiley   +1 more source

Current account benchmarks for central and eastern Europe: a desperate search? [PDF]

open access: yes
This paper examines two competing approaches for calculating current account benchmarks, i.e. the external sustainability approach á la Lane and Milesi-Ferretti (LM) versus the structural current accounts literature (SCA) based on panel econometric ...
Ca' Zorzi, Michele   +2 more
core  

The regulated firm: Effects of regulation on competence development and sustainable competitive advantage [PDF]

open access: yes, 2015
Sustainable competitive advantage (SCA) is a central tenet in strategic management theory. The effect of regulation on sustaining competitive advantages is widely neglected in literature.
Frohwein, Torsten
core  

Psychological and behavioral correlates of health anxiety and other anxiety phenomena in adolescence—A cross‐sectional study in the Copenhagen Child Cohort 2000

open access: yesJCPP Advances, EarlyView.
Abstract Background Health anxiety (HA) is characterized by impairing worry about being or becoming seriously ill. This cross‐sectional study aimed to explore psychological and behavioral correlates of HA compared to other anxiety phenomena in adolescents, that is, with respect to depression, physical symptoms, bodily dissatisfaction, health‐related ...
Charlotte Steen Duholm   +6 more
wiley   +1 more source

Why do attention‐deficit/hyperactive disorder and/or autism traits place adolescents at risk for depression? Protocol for a longitudinal comparison of the mediating role of emotion regulation deficits versus emotional burden

open access: yesJCPP Advances, EarlyView.
This paper details the protocol for the My Emotions and Me Over Time (MEMO) study, a longitudinal study exploring why ADHD and/or autism traits place adolescents at greater risk for depression. This study will explore two potential mediating factors in pathways to depression: emotional regulation deficits; and emotional burden.
Edmund J. S. Sonuga‐Barke   +10 more
wiley   +1 more source

Unraveling the Impact of Organizational Ambidexterity: The Role of Integration and Agility in Enhancing Performance amidst Supply Chain Disruptions

open access: yesGlobal Business and Organizational Excellence, EarlyView.
ABSTRACT The pandemic and supply chain disruptions are all examples of events that are forcing companies to do business differently. The study was conducted among 405 manufacturing and service companies in Malaysia and analyzed using PLS‐SEM. The role of integration and agility was key to determining how ambidexterity affected the performance of the ...
Muhammad Khalilur Rahman   +4 more
wiley   +1 more source

Impact of CYP2C19 Genotype Variants on PCSK9 Inhibitor Efficacy in Lipid‐Lowering Among Patients With Symptomatic Intracranial Atherosclerotic Stenosis

open access: yesLipids, EarlyView.
ABSTRACT Ischemic stroke is frequently associated with symptomatic intracranial atherosclerotic stenosis (sICAS), is a leading cause of global disability and mortality. Current guidelines recommend dual antiplatelet and intensive statin therapies. Proprotein convertase subtilisin 9/kexin type 9 (PCSK9) inhibitors have emerged as a potent lipid‐lowering
Chao Zhao   +5 more
wiley   +1 more source

Combining ability in bhindi [ Abelmoschus spp.] [PDF]

open access: yesElectronic Journal of Plant Breeding, 2009
Combining ability was estimated for six diverse okra genotypes or varieties by diallel analysis. The combininganalysis revealed that Arka Anamika was found to be a good general combiner for fruit number, fruit weight and fruit length.KL9 showed high gca ...
Divya Balakrishnan   +3 more
doaj  

An ultraviolet–visible spectroscopy system for studying real‐time pressure effects on enzyme activity

open access: yesLimnology and Oceanography: Methods, EarlyView.
Abstract Investigations of hydrostatic pressure effects on microbial enzymatic processing are challenging but critical for understanding element cycling in the world's oceans. In this study, we developed and tested a stainless‐steel pressure cell capable of withstanding up to 110 MPa of hydrostatic pressure (equivalent to ~ 11,000 m depth), featuring ...
Maria Papadimitraki   +6 more
wiley   +1 more source

The Polarizability Vector: A Polarimetric Observable for Characterizing Anisotropic Nanoparticles

open access: yesLaser &Photonics Reviews, EarlyView.
We find an overlooked observable in Nanophotonics that characterizes the optical response of anisotropic nanoparticles from simple polarimetry measurements. ABSTRACT The optical properties of anisotropic nanoparticles (NPs) are often characterized by two principal components of their polarizability tensor.
Jorge Olmos‐Trigo
wiley   +1 more source

Home - About - Disclaimer - Privacy