Results 161 to 170 of about 49,797 (259)

SCA27B in Brazil: frequency, phenotype and genotype-phenotype correlations. [PDF]

J Neurol
de Jesus Araujo Dias A, Silveira C, Vinagre AM, Bonadia LC, Santos NBS, Rezende TJR, Corazza LA, Pedroso JL, Barsottini OGP, de Lima FD, França Junior MC.   +10 more
europepmc   +1 more source

Is There a Difference in Occurrence of Complications Between Adults With Hemoglobin SS and Hemoglobin SC Disease: An Extended Systematic Review

European Journal of Haematology, EarlyView.
ABSTRACT Sickle cell disease (SCD) is characterized by both acute and chronic complications. The clinical manifestation of these complications differs between genotypes. Given the large amount of research already published, this systematic review aims to offer a complete overview of types of sickle cell complications between adults in the most common ...
Martijn van der Meer, Kim Velsink, Wing H. Tong, Jan W. Schoones   +3 more
wiley   +1 more source

Sudden cardiac arrest during endurance races: beyond final acceleration? [PDF]

Europace
Kato J.
europepmc   +1 more source

S‐Adenosylmethionine (SAM) hydrolases counter increased SAM epimerisation in thermophilic archaea

The FEBS Journal, EarlyView.
S‐Adenosyl‐l‐methionine (SAM) is a vital enzyme cofactor. Epimerisation at the sulfonium centre of biologically active (SS,SCα)‐SAM is driven by heat, yielding biologically inactive (RS,SCα)‐SAM. Here, two novel archaeal SAM hydrolases from the thermophilic Sulfolobus acidocaldarius and the halophilic Haloferax volcanii are shown to cleave (RS,SCα)‐SAM.
Agnes Bartels, Michael K. F. Mohr, Phillip Nußbaum, Marie Joest, Bianca Wassmer, Laurent Rasquin, Sonja‐Verena Albers, Jennifer N. Andexer   +7 more
wiley   +1 more source

Immune Imbalance in Sickle Cell Anemia: Flow Cytometric Insights Into Regulatory T Cells and Neutrophil Dynamics. [PDF]

J Clin Lab Anal
Ölçüoğlu R, Tanrıkulu F, Kılınç S, Çakmak E, Asma S, Boğa C, Özdoğu H, Pamuk İ.   +7 more
europepmc   +1 more source

PML as a neuroprotective guardian: Leveraging nuclear protein quality control to mitigate neurotoxicity of an ALS‐associated NEK1 variant

The FEBS Journal, EarlyView.
Insoluble protein aggregates are a hallmark of neurodegenerative diseases like amyotrophic lateral sclerosis (ALS). The ubiquitin–proteasome system (UPS) serves as a neuroprotective quality control mechanism that clears aggregates. PML nuclear bodies (NBs) were proposed to serve as hubs for SUMO‐primed ubiquitylation and degradation of misfolded ...
Tabea Stark, Stefan Müller
wiley   +1 more source

The heart's hidden blueprint: a rare variant of coronary artery origin from the right coronary cusp. [PDF]

J Cardiothorac Surg
Abdalla K, Alawneh K, Al-Bdour M, Abu-Salih AQ, Bakar SB.   +4 more
europepmc   +1 more source

Stimulating proteasomal degradation in human proteinopathies

The FEBS Journal, EarlyView.
The proteasome mediates the degradation of a wide range of proteins. Boosting proteasomal degradation may be beneficial in several disease contexts and can be achieved either by modulating proteasome activity or by improving substrate delivery. Proteasome activity can be enhanced by increasing proteasome abundance, inducing constitutive gate opening ...
Maria E. Gierisch, Enrica Barchi, Nico P. Dantuma   +2 more
wiley   +1 more source

SHARP: a hybrid metaheuristic approach for intelligent robotic path planning. [PDF]

Sci Rep
Fakhouri H, Alawadi S, Galozy A, Alkhabbas F, Ayyad M, Banihani I, Alkharabsheh K, Aladwan M.   +7 more
europepmc   +1 more source

A Consensus‐Based Glossary for Controversial Terminology in Root and Canal Anatomy

International Endodontic Journal, EarlyView.
ABSTRACT Aim To produce a glossary of controversial terminology relating to a variety of anatomical features of root canals. Materials and Methods A multi‐stage consensus process was designed and applied to generate definitions for controversial terms describing root and canal anatomy.
Hany Mohamed Aly Ahmed, Venkateshbabu Nagendrababu, Ali Keleş, Thomas Gerhard Wolf, Henry F. Duncan, Ove Andreas Peters, Paul Michael Howell Dummer, The Delphi Group for Terminology in Root Canal Anatomy, Abhishek Parolia, Alfredo Sierra‐Cristancho, Andrea Lisa Waber, Antonis Chaniotis, Azhar Iqbal, Blaine Murray Cleghorn, Cangül Keskin, Casper Jonker, Edgar Schäfer, Emmanuel J. N. L. Silva, Fatma Pertek Hatipoğlu, Francesc Abella Sans, Giampiero Rossi‐Fedele, Güldane Mağat, Hasan Mohsin Jawad Al‐Rammahi, Jaime Abarca, Jojo Kottoor, José Antonio González Sánchez, Lucila Piasecki, Manoel Damião Sousa‐Neto, Mohmed Isaqali Karobar, Mohamed Jamal, Moataz‐Bellah Alkhawas, Velmurugan Natanasabapathy, Nawar Naguib Nawar, Nessrin Taha, Rafael Chies Hartmann, Roshan Peiris, Shehabeldin Saber, Tiago Pimentel, Till Dammaschke, Yuan Gao   +39 more
wiley   +1 more source