Results 211 to 220 of about 72,995 (304)

Is There a Difference in Occurrence of Complications Between Adults With Hemoglobin SS and Hemoglobin SC Disease: An Extended Systematic Review

European Journal of Haematology, EarlyView.
ABSTRACT Sickle cell disease (SCD) is characterized by both acute and chronic complications. The clinical manifestation of these complications differs between genotypes. Given the large amount of research already published, this systematic review aims to offer a complete overview of types of sickle cell complications between adults in the most common ...
Martijn van der Meer, Kim Velsink, Wing H. Tong, Jan W. Schoones   +3 more
wiley   +1 more source

BCL11A and HBS1L-MYB polymorphisms, in association with hydroxyurea and sex, modulate fetal hemoglobin levels in individuals with sickle cell anemia in the western region of Bahia, Brazil. [PDF]

Mol Biol Rep
de Magalhães Filho MF, Santana ILR, da Silva PLP, Venancio LPR.   +3 more
europepmc   +1 more source

Exercise‐related microRNAs in Caenorhabditis elegans regulate calcium homeostasis and mitochondrial dynamics: Conserved pathways, divergent microRNAs

The FEBS Journal, EarlyView.
Exercise‐related microRNAs cel‐miR‐249‐3p and cel‐miR‐77‐5p in C. elegans regulate lifespan, fitness, mitochondrial morphology and membrane potential. Although lacking direct mammalian orthologs, H2O2‐induced microRNAs mmu‐miR‐181a‐5p and mmu‐miR‐378a‐3p regulate myogenesis, autophagy, mitochondrial content and respiration in murine myoblasts ...
Qin Xia, Jiwang Tang, José C. Casas‐Martinez, Penglin Li, Maria Borja‐Gonzalez, Leo R Quinlan, Katarzyna Goljanek‐Whysall, Brian McDonagh   +7 more
wiley   +1 more source

Association of endogenous hypercortisolism with hepatic hemangiomas in cushing's disease: a retrospective cohort study. [PDF]

BMC Endocr Disord
Zhao L, Liu J, Li N, Wei Y, Wang P, Li J, Zhang S.   +6 more
europepmc   +1 more source

S‐Adenosylmethionine (SAM) hydrolases counter increased SAM epimerisation in thermophilic archaea

The FEBS Journal, EarlyView.
S‐Adenosyl‐l‐methionine (SAM) is a vital enzyme cofactor. Epimerisation at the sulfonium centre of biologically active (SS,SCα)‐SAM is driven by heat, yielding biologically inactive (RS,SCα)‐SAM. Here, two novel archaeal SAM hydrolases from the thermophilic Sulfolobus acidocaldarius and the halophilic Haloferax volcanii are shown to cleave (RS,SCα)‐SAM.
Agnes Bartels, Michael K. F. Mohr, Phillip Nußbaum, Marie Joest, Bianca Wassmer, Laurent Rasquin, Sonja‐Verena Albers, Jennifer N. Andexer   +7 more
wiley   +1 more source

Modeling of solid oxide fuel cells and optimal parameter extraction at various operating data using an optimization method. [PDF]

PLoS One
Abaza A, El-Sehiemy RA, Ghoniem RM, Elbana MM, Bayoumi A.   +4 more
europepmc   +1 more source

Modification of the SCA Technique [PDF]

Interventions in Gynaecology and Women’s Healthcare, 2018
openaire   +1 more source

Institutional Trends in Penicillin Allergy: A New Era of Active Penicillin Allergy Delabeling

Clinical &Experimental Allergy, EarlyView.
Anna Brameli, Allison B. McCoy, Elizabeth McNeer, Leena Choi, Joanna L. Stollings, Grace Koo, Allison E. Norton, Milner Staub, George E. Nelson, James W. Antoon, Sophie E. Katz, Ritu Banerjee, Adam Wright, Elizabeth J. Phillips, Cosby A. Stone Jr.   +14 more
wiley   +1 more source

PML as a neuroprotective guardian: Leveraging nuclear protein quality control to mitigate neurotoxicity of an ALS‐associated NEK1 variant

The FEBS Journal, EarlyView.
Insoluble protein aggregates are a hallmark of neurodegenerative diseases like amyotrophic lateral sclerosis (ALS). The ubiquitin–proteasome system (UPS) serves as a neuroprotective quality control mechanism that clears aggregates. PML nuclear bodies (NBs) were proposed to serve as hubs for SUMO‐primed ubiquitylation and degradation of misfolded ...
Tabea Stark, Stefan Müller
wiley   +1 more source

Adiponectin levels during steady state and vaso-occlusive crisis in Nigerian children with sickle cell anaemia. [PDF]

Ann Hematol
Ulasi AE, Nri-Ezedi CA, Okpara HC, Ikefuna A, Ulasi TO.   +4 more
europepmc   +1 more source