Most in vitro cancer models lack cellular diversity, functional complexity, and clinical relevance. This work highlights the generation of an innovative dynamic tetraculture with autologous patient‐derived cells within a vascularized tumor‐on‐chip, as well as the recapitulation of endothelial anergy features induced by the tumor microenvironment ...
Christine Lansche+16 more
wiley +1 more source
Fish-derived biomaterials for tissue engineering: advances in scaffold fabrication and applications in regenerative medicine and cancer therapy. [PDF]
Jo S+5 more
europepmc +1 more source
Liquid Crystalline Networks Hamper the Malignancy of Cancer Cells
Liquid Crystalline Networks are used as scaffolds for the growth of A375 melanoma cells demonstrating to affect their malignancy. Indeed, only by contact, these materials reduces cell proliferation and colony formation capacity, while increasing the number of senescent cells and promoting the mesenchymal to epithelial transition.
Daniele Martella+9 more
wiley +1 more source
Scaffold Proteins in Fibrotic Diseases of Visceral Organs. [PDF]
Sun P, Yang L, Yu K, Wang J, Chao J.
europepmc +1 more source
This study presents a novel implantable drug delivery systemwith a biodegradable poly(caprolactone) membrane and compressed drug core forsustained release. These implantable devices deliver risperidone in vitro for 170 days and in vivo for 49 days in rats, showing promise for chronic conditions like schizophrenia.
Linlin Li+9 more
wiley +1 more source
Biomaterials-based approaches to mandibular tissue engineering: where we were, where we are, where we are going. [PDF]
Kennedy MM, Mikos AG.
europepmc +1 more source
This study reports a novel strategy for preparing a biocompatible adhesive hydrogel crosslinked with a muscle tissue‐derived extracellular matrix (MEM) for in situ muscle regeneration. As a natural crosslinker, MEM not only mediates combinatorial polymer networks but also stimulates satellite cells to induce a cell‐free therapeutic solution.
Eun Je Jeon+6 more
wiley +1 more source
Embryonic toxicology evaluation of novel <i>Cissus quadrangularis</i>, bioceramics and tendon extracellular matrix incorporated scaffolds for periodontal bone regeneration using zebrafish model. [PDF]
Balaji Ganesh S+5 more
europepmc +1 more source
Advancing Chronic Wound Healing through Electrical Stimulation and Adipose‐Derived Stem Cells
Chronic cutaneous wounds represent significant challenges due to delayed healing and resistance to conventional treatments. This review explores the potential of combining adipose‐derived stem cells with electrical stimulation to enhance wound healing.
Qiuyue Peng+5 more
wiley +1 more source
Injectable Composite Hydrogel Stents for Bone Defect Management with Enhanced Osteogenesis and Angiogenesis. [PDF]
Chen Z+5 more
europepmc +1 more source