Results 231 to 240 of about 1,777,748 (317)

The aspiration for scalable citizen-level interventions and the missing tests of countermessaging. [PDF]

Proc Natl Acad Sci U S A
Malka A, Druckman JN.
europepmc   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Secure and scalable dual blockchain and IPFS driven IoT ecosystem for next gen healthcare systems. [PDF]

Sci Rep
Mallick SR, Lenka RK, Sobhanayak S.
europepmc   +1 more source

Scalable image informatics [PDF]

, 2018
Fedorov, Dmitry, Manjunath, BS, Lang, Christian, Kvilekval, Kristian, G   +3 more
openaire   +2 more sources

Scale-free trees: The skeletons of complex networks [PDF]

, 2004
DH Kim, Jae Dong Noh, Hawoong Jeong
openalex   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Functional analysis of hyperautomation in construction for advancing efficiency and sustainability through process optimization and technological integration. [PDF]

Sci Rep
Baarimah SO, Mohammad A, Alyami H, Baarimah AO, Almujibah HR, Ramu MB.   +5 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

RISK: a next-generation tool for biological network annotation and visualization. [PDF]

Bioinformatics
Horecka I, Röst H.
europepmc   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source