Results 241 to 250 of about 1,777,748 (317)

RAPID-DASH: fast and efficient assembly of guide RNA arrays for multiplexed CRISPR-Cas9 applications. [PDF]

Synth Biol (Oxf)
Salaudeen AL, Mateyko N, de Boer CG.
europepmc   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Developing a smart and scalable tool for histopathological education-PATe 2.0. [PDF]

J Pathol Inform
Winter L, Artinger A, Böck H, Ramakrishnan V, Reible B, Albin J, Schüffler PJ, Raptis G, Brochhausen C.   +8 more
europepmc   +1 more source

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

FEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić, Darija Putar, Lucija Mijanović, Igor Weber   +3 more
wiley   +1 more source

Adaptive airspace allocation model for urban drone logistics using multi-objective optimization under uncertainty. [PDF]

Sci Rep
Zhu Y, Sun X, Hou T.
europepmc   +1 more source

Characterization of chromia scales formed in supercritical carbon dioxide

, 2017
Bruce A. Pint, Kinga A. Unocic, R. G. Brese, James R. Keiser   +3 more
openalex   +2 more sources

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Maintain the gains: methods to evaluate the sustainability and scalability of HIV-related prevention, care, and treatment programs. [PDF]

Curr Opin HIV AIDS
Rosen JG, Arnold T, Crane ME.
europepmc   +1 more source

Numerical Modelling of the Topographic Wetness Index: An Analysis at Different Scales

, 2011
Anderson Ruhoff, Nilza M.R. Castro, Alfonso Risso   +2 more
openalex   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source