Results 71 to 80 of about 41,122 (294)

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

A brief Review of the Scalar Field Dark Matter model [PDF]

open access: yes, 2012
In the last time the cold dark matter (CDM) model has suggested more and more that it is not able to describe all the properties of nearby galaxies that can be observed in great detail as well as that it has some problems in the mechanism by which matter
J. Magaña, T. Matos
semanticscholar   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Interacting quintessence in light of generalized uncertainty principle: cosmological perturbations and dynamics

open access: yesEuropean Physical Journal C: Particles and Fields, 2021
We consider a cosmological scenario endowed with an interaction between the universe’s dark components – dark matter and dark energy. Specifically, we assume the dark matter component to be a pressure-less fluid, while the dark energy component is a ...
Andronikos Paliathanasis   +4 more
doaj   +1 more source

EVOLUTION OF A DWARF SATELLITE GALAXY EMBEDDED IN A SCALAR FIELD DARK MATTER HALO [PDF]

open access: yes, 2014
The cold dark matter (CDM) model has two unsolved issues: simulations overpredict the satellite abundance around the Milky Way (MW) and it disagrees with observations of the central densities of dwarf galaxies which prefer constant density (core ...
V. Robles   +3 more
semanticscholar   +1 more source

Interacting diffusive unified dark energy and dark matter from scalar fields [PDF]

open access: yesThe European Physical Journal C, 2017
16 pages, many typos corrected.
Benisty, David, Guendelman, E.I.
openaire   +3 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

A new recipe for $$\Lambda $$ Λ CDM

open access: yesEuropean Physical Journal C: Particles and Fields, 2017
It is well known that a canonical scalar field is able to describe either dark matter or dark energy but not both. We demonstrate that a non-canonical scalar field can describe both dark matter and dark energy within a unified setting.
Varun Sahni, Anjan A. Sen
doaj   +1 more source

Hidden sector and gravity

open access: yesPhysics Letters B, 2020
In this paper, we consider a generic hidden sector which interacts only gravitationally with Standard Model particles. We show that quantum gravity leads to operators which can be probed with fifth force type experiments.
Xavier Calmet
doaj   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy