Results 51 to 60 of about 302,725 (292)

Targeting carbonic anhydrase IX/XII prevents the anti‐ferroptotic effect of stromal lactic acid in prostate carcinoma

Molecular Oncology, EarlyView.
In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella, Giuseppina Comito, Luigi Ippolito, Erica Pranzini, Marta Iozzo, Giulia Gangarossa, Francesca Virgilio, Silvia Bua, Alessio Nocentini, Giada Sandrini, Nicla Lorito, Marina Bacci, Gabriella Nesi, Pietro Spatafora, Sergio Serni, Claudiu T. Supuran, Andrea Morandi, Paola Chiarugi, Elisa Giannoni   +18 more
wiley   +1 more source

Understanding and measuring mechanical signals in the tumor stroma

FEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz, Chiara Cimmino, Maurizio Ventre, Alessandra Cambi   +3 more
wiley   +1 more source

WORKING PROGRAM FOR STUDENT COURSE «DISTRIBUTED COMPUTING SCHEDULING» AND METHODICAL SUPPORT DESCRIPTION

Современные информационные технологии и IT-образование, 2018
The article describes working program for student course B1.V.04 «Distributed Computing Scheduling» which is taught during second semester of master course 01.04.02 «Applied Mathematics and Informatics» of «Math modeling» specialty.
Yuliana A. Kryzhanovskaya
doaj   +1 more source

Quasi-Particles in Non-Commutative Field Theory [PDF]

, 2000
After a short introduction to the UV/IR mixing in non-commutative field theories we review the properties of scalar quasi-particles in non-commutative supersymmetric gauge theories at finite temperature.
Landsteiner, Karl
core   +1 more source

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

FEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi, Xin Gao, Takashi Gojobori   +2 more
wiley   +1 more source

An approach for coherent periodogram averaging of tilt‐series data for improved contrast transfer function estimation

FEBS Open Bio, EarlyView.
The contrast transfer function (CTF) is an imaging aberration that is a major resolution‐limiting factor in cryo‐electron microscopy (cryo‐EM). Precise CTF estimation is key to overcoming this limitation, but is particularly challenging in cryo‐electron tomography (cryo‐ET) data. Here, we present an approach for using geometric information to assist in
Sagar Khavnekar, William Wan
wiley   +1 more source

Quasi-exact solvable Dirac equation for the generalized Cornell potential plus a novel angle-dependent potential

Journal of Innovative Applied Mathematics and Computational Sciences
In this paper, we present the exact analytical solution of the Dirac equation with equal scalar and vector generalized Cornell potential plus a novel angle-dependent potential in the framework of quasi-exactly solvable problems.
Djahida Bouchefra, Badredine Boudjedaa
doaj   +1 more source

A note on the S-matrix bootstrap for the 2d O(N) bosonic model

Journal of High Energy Physics, 2018
In this work we apply the S-matrix bootstrap maximization program to the 2d bosonic O(N) integrable model which has N species of scalar particles of mass m and no bound states.
Yifei He, Andrew Irrgang, Martin Kruczenski   +2 more
doaj   +1 more source

On the computation of the term $w_{21}z^2\bar{z}$ of the series defining the center manifold for a scalar delay differential equation

, 2011
In computing the third order terms of the series of powers of the center manifold at an equilibrium point of a scalar delay differential equation, with a single constant delay $r>0,$ some problems occur at the term $w_{21}z^2\bar{z}.$ More precisely, in ...
Anca-Veronica Ion, J. Hale, J. Hale, T. Faria, W. Wischert   +4 more
core   +1 more source

Comprehensive end‐to‐end dosimetry audit for stereotactic body radiotherapy in spine, lung, and soft tissue

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose To create and conduct a comprehensive onsite end‐to‐end dosimetry audit to assess treatment accuracy of spine, lung, and soft tissue Stereotactic Body Radiotherapy (SBRT) across Australian and New Zealand (ANZ) radiotherapy centers. Methods The Australian Clinical Dosimetry Service (ACDS) anthropomorphic thorax phantom underwent a CT ...
Maddison Shaw, Andrew Alves, Jessica Lye, Joerg Lehmann, Fayz Kadeer, Sabeena Beveridge, Nicholas Hardcastle, Moshi Geso, Rhonda Brown   +8 more
wiley   +1 more source