Results 101 to 110 of about 559,341 (295)
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Journal of Mathematical and Fundamental Sciences, 2014 A special condition of Scherk-Schwarz and S^1/Z2 orbifold breaking brings about both a weakly-coupled SU(6) baby Higgs and a strongly-coupled will-be simplest little Higgs scalar in the near-brane of SU(3) x SU(3)x U(1).
Jusak Sali Kosasih +3 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Transport properties through graphene with sequence of alternative magnetic barriers and wells in the presence of time-periodic scalar potential. [PDF]
Sci Rep, 2021 Pakdel F, Maleki MA.
europepmc +1 more source
Thawing models in the presence of a generalized Chaplygin gas
, 2013 In this paper we consider a cosmological model whose main components are a scalar field and a generalized Chaplygin gas. We obtain an exact solution for a flat arbitrary potential.
del Campo, Sergio +5 more
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Massless Scalar QED with Non-minimal Chern Simons Coupling
, 1993 2+1 dimensional massless scalar QED with $(\phi^*\phi)^3$ scalar self-coupling is modified by the addition of a non- minimal Chern-Simons term that couples the dual of the electromagnetic field strength to the covariant current of the complex scalar ...
A. Fetter +23 more
core +2 more sources
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source