Results 111 to 120 of about 559,341 (295)
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Tachyonic fields in cosmology [PDF]
, 2014 The possibility of explanation of accelerated expansion of the Universe by tachyonic scalar fields which homogeneously fill the world is discussed. The dependences of potential and kinetic term on scale factor are deduced for the case of quintessential ...
Novosyadlyj, Bohdan
core
Scalar potential model progress
, 2007 Presented APS Apr07 meeting session s1 ...
openaire +2 more sources
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Effective Gravitational “Constant” in Scalar-(Curvature)Tensor and Scalar-Torsion Gravities
Universe, 2017 In theories where a scalar field couples nonminimally to gravity, the effective gravitational “constant” becomes dependent on the value of the scalar field.
Laur Järv
doaj +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Scalar field potentials for cosmology
Physical Review D, 2004 We discuss different aspects of modern cosmology through a scalar field potential construction method. We discuss the case of negative potential cosmologies and its relation with oscillatory cosmic evolution, models with a explicit interaction between dark energy and dark matter which address the coincidence problem and also the case of non-zero ...
Cardenas, VH, del Campo, S
openaire +4 more sources
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
E 9 exceptional field theory. Part I. The potential
Journal of High Energy Physics, 2019 We construct the scalar potential for the exceptional field theory based on the affine symmetry group E 9. The fields appearing in this potential live formally on an infinite-dimensional extended spacetime and transform under E 9 generalised ...
Guillaume Bossard +4 more
doaj +1 more source