Results 71 to 80 of about 3,208,254 (218)

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

MESOSCOPIC SCALE MINIMUM CUTTING THICKNESS MODEL AND ANALYSIS

open access: yesJixie qiangdu, 2022
Aiming at the minimum cutting thickness existing in mesoscopic cutting process, the formation mechanism of the minimum cutting thickness was described, and the theoretical model of minimum cutting thickness based on tool edge radius and friction ...
ZHU JiaWei, LEI XiaoBao, ZHANG Tao
doaj  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Blockchain Sharding Scalable Model of Adaptive Node Scale [PDF]

open access: yesJisuanji gongcheng
Sharding is one of the core technologies to address the scalability of blockchains. However, the existing sharding schemes generally adopt a static sharding method with a predetermined shards' scale, which does not match the open and low-threshold ...
Baoying LI, Zhihuai LI, Chengai WANG, Feng YANG
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

A Landscape-level Model for Ecosystem Restoration in the San Francisco Estuary and Its Watershed

open access: yesSan Francisco Estuary and Watershed Science, 2005
The CALFED Bay-Delta Program is an ambitious effort to restore ecosystems and improve reliability of ecosystem services in California’s Central Valley. Key issues for CALFED and its Ecosystem Restoration Program (ERP) include (1) meeting societal demand ...
Wim Kimmerer   +2 more
doaj  

Toward the development of an anisotropy-resolving subgrid-scale model for large eddy simulation

open access: yesJournal of Fluid Science and Technology, 2014
To improve the prediction accuracy of large eddy simulation, an anisotropy-resolving subgrid-scale (SGS) model is a promising strategy. Although an anisotropic term in this type of SGS model is known to effectively enhance unsteady motions of vortex ...
Tadashi OHTSUKA, Ken-ichi ABE
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

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