Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky +8 more
wiley +1 more source
Scale Space and Variational Methods in Computer Vision
Lecture Notes in Computer Science, 2015 Jean-François Aujol +2 more
semanticscholar +1 more source
A novel scale-space approach for multinormality testing and the k-sample problem in the high dimension low sample size scenario. [PDF]
PLoS One, 2019 Hindberg K, Hannig J, Godtliebsen F.
europepmc +1 more source
Glymphatic Dysfunction Reflects Post‐Concussion Symptoms: Changes Within 1 Month and After 3 Months
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Mild traumatic brain injury (mTBI) may alter glymphatic function; however, its progression and variability remain obscure. This study examined glymphatic function following mTBI within 1 month and after 3 months post‐injury to determine whether variations in glymphatic function are associated with post‐traumatic symptom severity ...
Eunkyung Kim +3 more
wiley +1 more source
Using Multiple Scale Space-Time Patterns in Variance-Based Global Sensitivity Analysis for Spatially Explicit Agent-Based Models. [PDF]
Comput Environ Urban Syst, 2019 Kang JY, Aldstadt J.
europepmc +1 more source
Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani +8 more
wiley +1 more source
Bayesian LASSO, scale space and decision making in association genetics. [PDF]
PLoS One, 2015 Pasanen L, Holmström L, Sillanpää MJ.
europepmc +1 more source
Discrete Scale-Space Theory and the Scale-Space Primal Sketch
, 1991 This thesis, within the subfield of computer science known as computer vision, deals with the use of scale-space analysis in early low-level processing of visual information. The main contributions comprise the following five subjects: The formulation of a scale-space theory for discrete signals.
openaire +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Accurate localization of epileptogenic tubers (ETs) in patients with tuberous sclerosis complex (TSC) is essential but challenging, as these tubers lack distinct pathological or genetic markers to differentiate them from other cortical tubers.
Tinghong Liu +11 more
wiley +1 more source
Scale-Space Theory : A Basic Tool for Analysing Structures at Different Scales
, 1994 Tony Lindeberg
semanticscholar +1 more source