Results 101 to 110 of about 23,299,567 (273)

Scaling of wet granular flows in a rotating drum

open access: yesEPJ Web of Conferences, 2017
In this work, we investigate the effect of capillary forces and particle size on wet granular flows and we propose a scaling methodology that ensures the conservation of the bed flow.
Jarray Ahmed   +3 more
doaj   +1 more source

Functional Assemblages of Collembola Determine Soil Microbial Communities and Associated Functions

open access: yesFrontiers in Environmental Science, 2019
Soil processes such as decomposition are mainly performed by soil biota. Although soils worldwide are extremely biodiverse, the relationship between decomposers (fauna and microorganisms), and ecosystem function is poorly understood.
Sékou F. M. Coulibaly   +6 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Jamming with magnetic composites

open access: yesNature Communications
The jamming transition—marked by dramatic changes in mechanical properties, such as stiffness and damping—enables programmable and adaptive structures for robotic applications.
Buse Aktaş   +9 more
doaj   +1 more source

Biallelic Inactivation of NSD1 Associated With Carcinogenesis in Sotos Syndrome

open access: yes
Pediatric Blood &Cancer, EarlyView.
Nicholas A. Borja   +8 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Teleoperated Magnetic Endoscopy: A Case Study and Perspective

open access: yesAdvanced Intelligent Systems
Teleoperated robotic surgery is a rapidly growing field that promises to overcome geographical barriers and share expertise over long distances for a variety of minimally invasive procedures.
Alexandre Mesot   +8 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The method of smelting metals from charge with low metal content in a furnace with bottom electrodes and the first laboratory studies

open access: yesMATEC Web of Conferences, 2018
Liquid phase smelting reduction process for utilization of ferrous waste in the electric furnace with stationary bottom electrodes by carbon-thermal reduction is proposed and tested in laboratory conditions.
Kazak Oleg, Starodumov Ilya
doaj   +1 more source

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