Results 101 to 110 of about 16,600,501 (304)

THERMOMETER SCALES [PDF]

Science, 1916
n ...
openaire   +3 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Towards sustainable additive manufacturing: Enhanced productivity via numerical-experimental melt pool engineering in laser powder bed fusion of Ti-alloy

Journal of Materials Research and Technology
Laser Powder Bed Fusion (LPBF) offers a promising approach for creating metallic components with tailored properties. However, low production speed and high manufacturing costs remain challenges.
Mahyar Hasanabadi, Hamed Asgari, Nadia Azizi, Hamid Aghajani, Tatevik Minasyan, Ehsan Toyserkani   +5 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

The method of smelting metals from charge with low metal content in a furnace with bottom electrodes and the first laboratory studies

MATEC Web of Conferences, 2018
Liquid phase smelting reduction process for utilization of ferrous waste in the electric furnace with stationary bottom electrodes by carbon-thermal reduction is proposed and tested in laboratory conditions.
Kazak Oleg, Starodumov Ilya
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Exploratory factor analysis yields grouping of brain injury biomarkers significantly associated with outcomes in neonatal and pediatric ECMO

Scientific Reports
In this two-center prospective cohort study of children on ECMO, we assessed a panel of plasma brain injury biomarkers using exploratory factor analysis (EFA) to evaluate their interplay and association with outcomes.
Victoria Huang, Jennifer Roem, Derek K. Ng, Jamie McElrath Schwartz, Allen D. Everett, Nikhil Padmanabhan, Daniel Romero, Jessica Joe, Christopher Campbell, George B. Sigal, Jacob N. Wohlstadter, Melania M. Bembea   +11 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Object Detection at the Optimal Scale with Hidden State Shape Models [PDF]

, 2006
Hidden State Shape Models (HSSMs) [2], a variant of Hidden Markov Models (HMMs) [9], were proposed to detect shape classes of variable structure in cluttered images. In this paper, we formulate a probabilistic framework for HSSMs which provides two major
Athitsos, Vassilis, Betke, Margrit, Sclaroff, Stan, Wang, Jingbin   +3 more
core   +1 more source

Enhancement of small-scale turbulent dynamo by large-scale shear

, 2017
Small-scale dynamos are ubiquitous in a broad range of turbulent flows with large-scale shear, ranging from solar and galactic magnetism to accretion disks, cosmology and structure formation.
Brandenburg, Axel, Rogachevskii, Igor, Singh, Nishant K.   +2 more
core   +1 more source