Results 261 to 270 of about 1,443 (288)

Structural Polymorphism of polyG Inclusions Revealed by In Situ Cryo‐Electron Tomography

open access: yesAdvanced Science, EarlyView.
Correlative cryo‐electron tomography in primary cortical neurons and NIID mouse brain tissue reveals that polyG inclusions are interconnected ribbon‐like assemblies rather than canonical amyloid fibrils. Multiple compartment‐specific ribbon states show distinct 26S proteasome accessibility, while cytoplasmic ribbons contact and deform ER‐like ...
Yunwen Qian   +12 more
wiley   +1 more source

Nonreciprocal buckling makes active filaments polyfunctional. [PDF]

open access: yesProc Natl Acad Sci U S A
Al-Izzi SC   +7 more
europepmc   +1 more source

PolyG Fibrils Coalesce Into Nuclear Ribbons That Engage Proteostasis Machinery in Neuronal Intranuclear Inclusion Disease

open access: yesAdvanced Science, EarlyView.
In NIID, expanded NOTCH2NLC repeats give rise to nuclear polyG inclusions. Tracer‐guided in situ cryo‐electron tomography enables cross‐scale structural analysis from mouse brain to native neuronal nuclei, revealing dense‐core/peripheral‐halo inclusions built from compact polyG ribbons.
Hui Dong   +13 more
wiley   +1 more source

Kirigami‐Cut Pattern Designs for the Enhancement of Sensing Performance Induced by Programmable Out‐of‐Plane Deformation

open access: yesAdvanced Science, EarlyView.
Different kirigami patterns are proposed and the parameters are optimized by comparing the out‐of‐plane deformation behavior. Then, the proposed patterns are fabricated on PVDF film using laser technology. The deformed kirigami‐cut PVDF is embedded into PDMS to construct pressure senor.
Xiaodong Huang   +6 more
wiley   +1 more source

Marginally outer trapped tubes in de Sitter spacetime. [PDF]

open access: yesLett Math Phys
Mars M   +3 more
europepmc   +1 more source

Polarization Engineering in Vinylene‐Linked COFs Toward Efficient Neuromorphic Computing

open access: yesAdvanced Science, EarlyView.
A vinyl‐linked covalent organic framework (COF‐DIBPY) was synthesized on a conductive substrate for memristor applications. Redox reactions and bromide migration enable low‐voltage (0.5V) conductance switching with high analog on/off ratio (15.7). The device was further integrated into a speech emotion recognition system for acoustic simulation and ...
Hao Wang   +5 more
wiley   +1 more source

Topological photonic crystal fiber. [PDF]

open access: yesSci Adv
Zhu B   +10 more
europepmc   +1 more source

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