Results 161 to 170 of about 81,520 (219)

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

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On the scale effect and scale-up in the column apparatuses. 2. Scale effect modeling

International Journal of Heat and Mass Transfer, 2009
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Panayotova, K., Doichinova, M., Boyadjiev, Chr.   +2 more
openaire   +2 more sources

A note on scale effects

Review of Economic Dynamics, 2004
Abstract This note presents a simple extension of the seminal Romer (1990, Journal of Political Economy 98(2), 71–102) paper. Allowing for elasticity of substitution between labor and capital to be different from one (CES production function instead of Cobb–Douglas), the following results are obtained.
openaire   +1 more source

Scaled Quantum effects

Chaos, Solitons & Fractals, 2004
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +1 more source

Effectiveness of a calculus scaling gel

Journal of Clinical Periodontology, 1994
Abstract. This study evaluated the effect of a calculus scaling gel (SofScale TM) on time and ease of the scaling procedure in a double‐blind, split‐mouth clinical study of 32 subjects. The Volpe‐Manhold calculus index was used to quantify the distribution and amount of calculus deposition on the lingual aspect of the man‐dibular 6 anterior teeth at ...
G B, Maynor, R S, Wilder, S C, Mitchell, J D, Moriarty   +3 more
openaire   +2 more sources

Weak-scale effective supersymmetry

Physical Review Letters, 1990
The idea of supersymmetry at the weak scale should be tested without regard to the Planck-scale origin of any specific model. A class of low-energy effective supersymmetric theories is derived from four assumptions: minimal field content, {ital R}-parity conservation, absence of quadratic divergences, and naturalness of near-flavor conservation ...
, Hall, , Randall
openaire   +2 more sources